A randomized prospective study of a hydroactive dressing vs conventional treatment after shave biopsy excision

Phillips, Tania J.

doi:10.1001/archderm.129.7.859

Cited by 7 publications

(7 citation statements)

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“…Goodness‐of‐fit tests revealed that hazard ratios could not be assumed constant over time, indicating that wound healing is dynamic, and not linear over time. We, therefore, investigated the likelihood of healing in the following three periods: (1) within the first 3 weeks of therapy, during which superficial, nonproblematic, uncomplicated wounds were expected to heal; (2) 3 weeks–3 months of therapy, representing the intermediate period, in which superficial, uncomplicated, fast‐healing wounds were no longer included, and the wound chronicity is not completely established; and (3) after 3 months’ therapy, representing established chronicity . There was no significant evidence against the extended Cox model, and it was thus used for further analysis.…”

Section: Methodsmentioning

confidence: 99%

Wound healing and all‐cause mortality in 958 wound patients treated in home care

Zarchi

Martinussen

Jemec

2015

Wound Repair Regeneration

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Skin wounds are associated with significant morbidity and mortality. Data are, however, not readily available for benchmarking, to allow prognostic evaluation, and to suggest when involvement of wound-healing experts is indicated. We, therefore, conducted an observational cohort study to investigate wound healing and all-cause mortality associated with different types of skin wounds. Consecutive skin wound patients who received wound care by home-care nurses from January 2010 to December 2011 in a district in Eastern Denmark were included in this study. Patients were followed until wound healing, death, or the end of follow-up on December 2012. In total, 958 consecutive patients received wound care by home-care nurses, corresponding to a 1-year prevalence of 1.2% of the total population in the district. During the study, wound healing was achieved in 511 (53.3%), whereas 90 (9.4%) died. During the first 3 weeks of therapy, healing was most likely to occur in surgical wounds (surgical vs. other wounds: adjusted hazard ratio [AHR] 2.21, 95% confidence interval 1.50-3.23), while from 3 weeks to 3 months of therapy, cancer wounds, and pressure ulcers were least likely to heal (cancer vs. other wounds: AHR 0.12, 0.03-0.50; pressure vs. other wounds: AHR 0.44, 0.27-0.74). Cancer wounds and pressure ulcers were further associated with a three times increased probability of mortality compared with other wounds (cancer vs. other wounds: AHR 3.19, 1.35-7.50; pressure vs. other wounds: AHR 2.91, 1.56-5.42). In summary, the wound type was found to be a significant predictor of healing and mortality with cancer wounds and pressure ulcers being associated with poor prognosis.

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Section: Methodsmentioning

confidence: 99%

Wound healing and all‐cause mortality in 958 wound patients treated in home care

Zarchi

Martinussen

Jemec

2015

Wound Repair Regeneration

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“…We also found that, in both types of wounds, hydrocolloid occlusive dressings decreased pain and did not increase the risk of infection compared to the control dressing, which was a standard adhesive bandage placed over antibiotic ointment. 20 Phillips et al 21 conducted a similar study a few years later, treating partial-thickness biopsy wounds with either a hydrocolloid dressing or a standard adhesive bandage and antibiotic ointment, and they found no difference in healing time. The reason for the differing findings of the two studies is not clear, although different hydrocolloids were used by each group.…”

Section: Issues Regarding the Clinical Use Of Occlusive Dressingsmentioning

confidence: 99%

“…Phillips et al 21 conducted a similar study a few years later, treating partial‐thickness biopsy wounds with either a hydrocolloid dressing or a standard adhesive bandage and antibiotic ointment, and they found no difference in healing time. The reason for the differing findings of the two studies is not clear, although different hydrocolloids were used by each group.…”

Section: Issues Regarding the Clinical Use Of Occlusive Dressingsmentioning

confidence: 99%

Moist Wound Healing with Occlusive Dressings: A Clinical Focus

Eaglstein

2001

Dermatol Surg

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The concept of moist wound healing, which is facilitated by the application of occlusive dressings, dates back to 1615 BC, and the technique is currently supported by a relatively large volume of data. It is clear that occlusive dressings are in many cases associated with more rapid reepithelialization, a reduced risk of infection, and more rapid wound healing than the alternatives. Nevertheless, many clinicians have been slow to accept this therapeutic technique. This article traces the history of moist wound healing from its earliest inception, examines the theoretical mechanisms of its effect, and explores its advantages and disadvantages. It also reviews the literature supporting the use of occlusive dressings in a variety of wound settings and examines the possible reasons behind the apparent reluctance on the part of the medical community to accept a potentially valuable therapy.

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“…These findings led to the use of prophylactic topical antibiotics as part of the standard of care for surgical procedures. Today, most directions for wound care after minor procedures (i.e., shave biopsy) include cleaning of the site, application of a topical antibiotic ointment, and covering with a dressing (20,21).…”

Section: Discussionmentioning

confidence: 99%

Update on topical antibiotics in dermatology

Drucker

2012

Dermatologic Therapy

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Topical antibiotics are used for various purposes in dermatology. Some of the most common uses include treatment of acne, treatment and prevention of wound infection(s), impetigo or impetiginized dermatitis, and staphylococcal nasal carrier state. It is important for the dermatologist to be familiar with the spectrum of activity, the mechanism of action, and the variables that may interfere with the antibiotic of choice. The following discussion will review an update on topical antibiotic use in acne, wound care, impetigo, and in staphylococcal nasal carriers.

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A randomized prospective study of a hydroactive dressing vs conventional treatment after shave biopsy excision

Cited by 7 publications

References 0 publications

Wound healing and all‐cause mortality in 958 wound patients treated in home care

Wound healing and all‐cause mortality in 958 wound patients treated in home care

Moist Wound Healing with Occlusive Dressings: A Clinical Focus

Update on topical antibiotics in dermatology

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