A Randomized-Controlled Trial Pilot Study Examining the Effect of Pelvic Floor Muscle Training on the Irisin Concentration in Overweight or Obese Elderly Women with Stress Urinary Incontinence

Abstract

Objective. This study aimed to examine the effect of pelvic floor muscle training on the irisin (Ir) concentration in overweight or obese elderly women with stress urinary incontinence. Methods. The number of participants included in analysis was 49: 28 women in the experimental group and 21 women in the control group. The experimental group (EG) underwent pelvic floor muscle training, whereas no therapeutic intervention was applied to the control group (CG). Irisin concentration, severity of urinary incontinence (RUIS), and body mass index (BMI) were measured in all women at the initial and final assessments. Results. By comparing the initial and final assessment results we have been able to demonstrate statistically significant differences in the measured variables in the experimental group. No statistically significant differences in the measured variables were reported for the control group at the initial and final assessments. Moderate negative correlation was observed between the BMI results with the irisin concentration results in the EG at the initial assessment and no correlation at the final assessment. Weak positive correlation was observed between the BMI results with the irisin concentration in the CG at the initial and final assessment. Conclusion. Further studies are necessary to observe the regulation of irisin concentration and explain mechanisms underlying these effects.

Assessment of the Effectiveness of Pelvic Floor Muscle Training (PFMT) and Extracorporeal Magnetic Innervation (ExMI) in Treatment of Stress Urinary Incontinence in Women: A Randomized Controlled Trial

“…e RUIS scores showed a statistically significant improvement in the urinary incontinence severity in both the PFMT group (EG1) and the ExMI group (EG2). Similar results were obtained in our previous studies [6,8,14].…”

Long-Term Effect of Exercise on Irisin Blood Levels—Systematic Review and Meta-Analysis

“…More specifically, our study shows that endurance training and combined training increase irisin blood levels in obese older females [26], combined training in obese middle-aged males [33], endurance [46,68] and resistance exercise [49] in young obese adult males, and resistance exercise training in obese older males [52,76]. Moreover, exercise and dietary lifestyle programs demonstrated increases in irisin blood levels in obese children [31], and pelvic floor muscle training increased irisin in obese older females with stress urinary incontinence [80]. As mentioned in the introduction, irisin is secreted from muscles in response to exercise and is believed to positively affect many physiological processes in the human body, such as inhibition of adipogenesis in the adipose tissue [83].…”

Effectiveness of Magnetic Stimulation in the Treatment of Urinary Incontinence: A Systematic Review and Results of Our Study

“…Forty-five articles were excluded for any of the following reasons: they were not in English, they were review articles or meta-analyses, only males were subjects of the research, they were case reports or they were conference abstracts, or there were no possibilities for analyzing the success rate of the treatment. Thus 12 articles [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ], summarized in Table 1 , Table 2 , Table 3 , Table 4 and Table 5 , represented the object of this review.…”