A randomized controlled trial of homeopathic treatment of weaned piglets in a commercial swine herd

Soto, Francisco Rafael Martins; Vuaden, Erlete Rosalina; Coelho, Cardoso; Benites, Nilson Roberti; Bonamin, Leoni Villano; Azevêdo, Sérgio Santos de

doi:10.1016/j.homp.2008.09.002

Cited by 18 publications

(20 citation statements)

References 8 publications

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“…The reasons listed for application of homeopathic remedies were predominantly prevention (n=10). Three studies addressed fertility disorders in sows (Day 1984, Seifert 1987, Drösemeier 1989), three dealt with respiratory infections (Schütte 1991 [two trials], Albrecht and Schütte 1999) and three with diarrhoea (Soto and others 2008, Coelho and others 2009, Camerlink and others 2010), while two focused on growth promotion(Guajardo-Bernal and others 1996, Da Silva and others 2011) and one simply aimed for a good general health (Schütte 2003). The three disease complexes mentioned are among the most common reasons for the use of antibiotics on pig farms in practice (Christensen and others 1995, Petersen and others 2008).…”

Section: Species-specific Resultsmentioning

confidence: 99%

“…The weight recorded differed between the groups within the study period, but as there was no control group, no clear outcome could be concluded. Studies by Soto and others (2008), Coelho and others (2009) and Camerlink and others (2010) aimed to prevent diarrhoea in piglets. Coelho and others (2009) and Camerlink and others (2010) performed a double and single blind RCT, respectively.…”

Section: Species-specific Resultsmentioning

confidence: 99%

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Efficacy of homeopathy in livestock according to peer‐reviewed publications from 1981 to 2014

Doehring

Sundrum

2016

Veterinary Record

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Homeopathy is widely used in livestock, especially in order to reduce the use of antibiotics, although it is often seen as controversial. A comprehensive literature review has been conducted to assess the efficacy of homeopathy in cattle, pigs and poultry. Only peer-reviewed publications dealing with homeopathic remedies, which could possibly replace or prevent the use of antibiotics in the case of infective diseases or growth promotion in livestock were included. Search results revealed a total number of 52 trials performed within 48 publications fulfilling the predefined criteria. Twenty-eight trials were in favour of homeopathy, with 26 trials showing a significantly higher efficacy in comparison to a control group, whereas 22 showed no medicinal effect. Cure rates for the treatments with antibiotics, homeopathy or placebo varied to a high degree, while the remedy used did not seem to make a big difference. Looking at all the studies, no study was repeated under comparable conditions. Consequently, the use of homeopathy currently cannot claim to have sufficient prognostic validity where efficacy is concerned. When striving for high therapeutic success in treatment, the potential of homeopathy in replacing or reducing antibiotics can only be validated if evidence of efficacy is confirmed by randomised controlled trials under modified conditions.

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Section: Species-specific Resultsmentioning

confidence: 99%

Section: Species-specific Resultsmentioning

confidence: 99%

Efficacy of homeopathy in livestock according to peer‐reviewed publications from 1981 to 2014

Doehring

Sundrum

2016

Veterinary Record

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“…However, several studies present data that homeopathic remedies are not operating though a placebo response. Several reports, for example, show that homeopathic remedies are effective in treating infants, comatose patients and animals [7][8][9][10][11][12][13] induce oestrus in cows [14]. Another report has shown that homeopathic remedies might be trigger cytolytic activity in breast cancer cells maintained in culture [15].…”

Section: Ethical and Regulatory Issues Regarding Homeopathymentioning

confidence: 99%

Homeopathic Treatment of Infertility: A Medical and Bioethical Perspective

Masiello

Loike

2017

IJCAM

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Homoeopathy has a significant clinical history, tracing its roots back to the ancient physician Hippocrates. In the last 30 years, it has surged in popularity among those seeking alternative forms of medical treatment. Countering this increase in popularity, some recent meta-analyses have suggested that the therapeutic claims of homeopathy lack scientific justification. A popular area of homeopathic application is infertility. In this paper we review the homeopathic approach and the bioethical implications to infertility, and propose that monitoring the effects of homeopathic remedies on infertile women may be as effective method to assess the efficacy of this form of alternative medicine. Keywords:

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“…In broiler chicken, thymulin 5CH offered into the drinking water since the first day of life improved the weight gain, survival, and productivity indexes at slaughter time [13]. Important to point out that offering homeopathic medicines into the drinking water represents a good, cheap, and easy tool to treat farm animals [20]. …”

Section: Introductionmentioning

confidence: 99%

Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model

Bonamin

Sato

Neto

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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The present study analyzed the immune modulation mechanisms of thymulin 5CH in a granuloma experimental model. Male adult Balb/c mice were inoculated with BCG into the footpad to induce granuloma, which was quantitatively evaluated. The phenotypic characterization of phagocyte, T- and B-lymphocyte populations in the peritoneum, and local lymph node was done by flow cytometry. During all experimental periods, thymulin 5CH and vehicle (control) were given ad libitum to mice, diluted into the drinking water (1.6 × 10−17 M). After 7 days from inoculation, thymulin-treated mice presented reduction in the number of epithelioid cytokeratine-positive cells (P = 0.0001) in the lesion, in relation to young phagocytes. After 21 days, the differentiation of B1 peritoneal stem cells into phagocytes reached the peak, being higher in thymulin-treated mice (P = 0.0001). Simultaneously, the score of infected phagocytes in the lesion decreased (P = 0.001), and the number of B1-derived phagocytes, CD4+ and CD8+ T lymphocytes in the local lymph node increased in relation to control (P = 0.0001). No difference was seen on the CD25+ Treg cells. The results show that thymulin 5CH treatment is able to improve the granuloma inflammatory process and the infection remission, by modulating local and systemic phagocyte differentiation.

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A randomized controlled trial of homeopathic treatment of weaned piglets in a commercial swine herd

Cited by 18 publications

References 8 publications

Efficacy of homeopathy in livestock according to peer‐reviewed publications from 1981 to 2014

Efficacy of homeopathy in livestock according to peer‐reviewed publications from 1981 to 2014

Homeopathic Treatment of Infertility: A Medical and Bioethical Perspective

Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model

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