A quantified description of the interactions between the native cardiovascular system and femoro‐femoral versus femoro‐axillary extracorporeal life support using descending thoracic aorta velocity time integral

Andrei, Ștefan; Tran-Dinh, Alexy; Provenchère, Sophie; Lortat‐Jacob, Brice; Ghodbane, Walid; Montravers, Philippe; Longrois, Dan

doi:10.1111/aor.13411

Cited by 8 publications

(3 citation statements)

References 33 publications

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“…A low pulse pressure during VA reflects a low native cardiac output [ 28 ]. Retrograde aortic flow into the aorta during VA ECMO can cause upper body hypoxemia in relation to the competitive flows between the native blood flow and the VA ECMO blood flow (Q EC ), particularly in the case of the commonly used peripheral femoro-femoral cannulation [ 29 , 30 , 31 ]. Several mixed blood zones have been observed because the mixed blood zone location depends on native heart and lung functionality and on the hemodynamic support provided by VA ECMO [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Determinants of Arterial Pressure of Oxygen and Carbon Dioxide in Patients Supported by Veno-Arterial ECMO

Andrei

Nguyen

Berthoud

et al. 2022

JCM

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Background: The present study aimed to assess the determinants of arterial partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2) in the early phase of veno-arterial extracorporeal membrane oxygenation (VA ECMO) support. Even though the guidelines considered both the risks of hypoxemia and hyperoxemia during ECMO support, there are a lack of data concerning the patients supported by VA ECMO. Methods: This is a retrospective, monocentric, observational cohort study in a university-affiliated cardiac intensive care unit. Hemodynamic parameters, ECMO parameters, ventilator settings, and blood gas analyses were collected at several time points during the first 48 h of VA ECMO support. For each timepoint, the blood samples were drawn simultaneously from the right radial artery catheter, VA ECMO venous line (before the oxygenator), and from VA ECMO arterial line (after the oxygenator). Univariate followed by multivariate mixed-model analyses were performed for longitudinal data analyses. Results: Forty-five patients with femoro-femoral peripheral VA ECMO were included. In multivariate analysis, the patients’ PaO2 was independently associated with QEC, FDO2, and time of measurement. The patients’ PaCO2 was associated with the sweep rate flow and the PpreCO2. Conclusions: During acute VA ECMO support, the main determinants of patient oxygenation are determined by VA ECMO parameters.

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Section: Discussionmentioning

confidence: 99%

Determinants of Arterial Pressure of Oxygen and Carbon Dioxide in Patients Supported by Veno-Arterial ECMO

Andrei

Nguyen

Berthoud

et al. 2022

JCM

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“…Axillary cannulation, with its anterograde aortic blood outflow, could attenuate the impact of VA-ECMO on LV afterload. In an elegant study, using Doppler evaluation of the descending thoracic aortic blood flow, Andrei and colleagues 16 demonstrated that in an axillary-femoral configuration, the ECMO flow and the native LV outflow were additive. In comparison, in a femoro-femoral configuration, ECMO flow and the native LV outflow were competitive.…”

Section: Influence Of the Arterial Cannulation Site On Left Ventricul...mentioning

confidence: 99%

Controversies in extracorporeal membrane oxygenation: Immediate versus watchful waiting for venoarterial extracorporeal membrane oxygenation venting

Cavayas¹,

Noly²,

Singh³

et al. 2021

JTCVS Open

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“…Stefan Andrei et al of the Université Paris Sorbonne, Paris, France evaluated if the axillary and femoral arterial cannulation site may have different effects on left ventricular (LV) outflow. Seven patients with femoro‐axillary ECLS and 4 patients with femoro‐femoral ECLS were prospectively studied using the Pulse‐wave Doppler velocity time integral (VTI) in the descending thoracic aorta (DTA VTI) at different short‐time variations of ECLS flow rates during the ECLS weaning process.…”

Section: Cardiopulmonary Support and Membrane Oxygenationmentioning

confidence: 99%

Artificial Organs 2019: A year in review

Malchesky¹

2020

Artificial Organs

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In this Editor’s Review, articles published in 2019 are organized by category and summarized. These provide a brief reflection of the research and progress in artificial organs intended to advance and better human life while providing insight for continued application of these technologies and methods. Artificial Organs continues in the original mission of its founders “to foster communications in the field of artificial organs on an international level.” Artificial Organs continues to publish developments and clinical applications of artificial organ technologies in this broad and expanding field of organ Replacement, Recovery, and Regeneration from all over the world. Peer‐reviewed Special Issues this year included contributions from the 14th International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion edited by Dr Akif Undar, and the 26th Congress of the International Society for Mechanical Circulatory Support edited by Dr Minoru Ono and Dr Francesco Moscato. Additionally, important editorials highlighted the need for sustainability in hemodialysis, challenges and opportunities in mechanical circulatory support, progress in artificial pancreas development, historical perspectives on ventilators and dialysis, tissue engineering for cardiac support, and regional updates from India and China. Our Pioneer Series continues to highlight the many researchers who created this field of study. This year we debuted a new series entitled “Recent Progress in Artificial Organs” prepared by Vakhtang Tchantchaleishvili and Elizabeth Maynes of Thomas Jefferson University, Philadelphia, PA, USA. This series highlights recent advances and new developments in the field. We take this time also to express our gratitude to our authors for contributing their work to this journal. We offer our very special thanks to our reviewers who give so generously of their time and expertise to review, critique, and especially provide meaningful suggestions to the author’s work. Without our dedicated expert reviewers, the quality expected from such a journal would not be possible. We also express our special thanks to our Publisher, John Wiley & Sons, for their expert attention and support in the production Artificial Organs. We look forward to reporting further advances in the coming years.

show abstract

A quantified description of the interactions between the native cardiovascular system and femoro‐femoral versus femoro‐axillary extracorporeal life support using descending thoracic aorta velocity time integral

Cited by 8 publications

References 33 publications

Determinants of Arterial Pressure of Oxygen and Carbon Dioxide in Patients Supported by Veno-Arterial ECMO

Determinants of Arterial Pressure of Oxygen and Carbon Dioxide in Patients Supported by Veno-Arterial ECMO

Controversies in extracorporeal membrane oxygenation: Immediate versus watchful waiting for venoarterial extracorporeal membrane oxygenation venting

Artificial Organs 2019: A year in review

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