A Prospective Trial Comparing Lymphangiogram, Cross-Sectional Imaging, and Positron Emission Tomography Scan in the Detection of Lymph Node Metastasis in Locally Advanced Cervical Cancer

Small, William; Vern, Tamara Z.; Rademaker, Alfred; Nemcek, Albert A.; Spies, Stewart; Schink, Julian C.; Singh, Diljeet K.; Lurain, John R.

doi:10.1097/coc.0b013e31819fdfae

Cited by 6 publications

(2 citation statements)

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“…50 A prospective study evaluated the use of lymphangiography, CT/MRI, and PET imaging for the detection of lymph node metastasis in patients receiving primary chemoradiotherapy for cervical cancer. 51 Agreement between imaging was most consistent in the common iliac LN (p < 0.001) and the least consistent in the PALN (p Z 0.41). Disease-free and overall survival rates were most accurately predicted by PET.…”

Section: Comparisons Between Different Imaging Modalitiesmentioning

confidence: 90%

“…Disease-free and overall survival rates were most accurately predicted by PET. 51 A Korean retrospective study (n Z 83) reviewed patients with cervical cancer who had undergone both preoperative MRI and PET/CT before radical surgery and lymphadenectomy. The sensitivity, specificity, and accuracy of detecting LN metastasis were 64.3%, 69.1%, and 67.5% for MRI and 28.6%, 83.6%, and 65.1% for PET/CT, respectively.…”

Section: Comparisons Between Different Imaging Modalitiesmentioning

confidence: 99%

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Molecular imaging in the management of cervical cancer

Lai

Yen

2012

Journal of the Formosan Medical Association

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Positron emission tomography (PET), magnetic resonance imaging (MRI), and integrated 18-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography are valuable techniques for assessing prognosis, treatment response after the completion of concurrent chemoradiation, suspicious or documented recurrence, unexplained post therapy elevations in tumor markers, and the response to salvage treatment when managing cervical cancer. However, PET plays a limited role in the primary staging of MRI-defined node-negative patients. Currently, (18)F-FDG is still the only tracer approved for routine use, but several novel targeting PET compounds, high-Tesla MRI machines, diffusion-weighted imaging without contrast, and dynamic nuclear polarized-enhanced (13)C-MR spectroscopic imaging may hold promising applications.

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Section: Comparisons Between Different Imaging Modalitiesmentioning

confidence: 90%

Section: Comparisons Between Different Imaging Modalitiesmentioning

confidence: 99%