A prospective, randomized study in critically ill patients using the Oligon Vantex® catheter

Corral, Luisa; Nolla-Salas, M; Ibáñez-Nolla, Jordi; Leon, M. A. Mendes de; Díaz, Rosa; Martín, M.C.; Iglesia, Raquel; Catalan, Rosa-Maria

doi:10.1016/j.jhin.2003.07.001

Cited by 61 publications

(43 citation statements)

References 39 publications

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“…Two trials used guidewires in all exchanges 61,72 and one trial in approximately 50% of exchanges (control group = 41%, treatment group = 53%). 58 The remaining four trials used guidewires in less than 50% of exchanges (average across groups of 30%, 18 34%, 62 6.6% 13 and 15.5% 14 ).…”

Section: Number Of Cvcs Exchanged Over a Guidewirementioning

confidence: 99%

See 1 more Smart Citation

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Hockenhull¹,

Dwan²,

Boland³

et al. 2008

Health Technol Assess

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment ProgrammeT he Health Technology Assessment (HTA) Programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA Programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA Programme is needs-led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in the NHS, the public and consumer groups and professional bodies such as royal colleges and NHS trusts. These sugges...

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Section: Number Of Cvcs Exchanged Over a Guidewirementioning

confidence: 99%

“…By July 2005 a further 11 trials had been published. [8][9][10][11][12][13][14][15][16][17][18] This review was commissioned to determine the clinical effectiveness and cost-effectiveness of CVCs treated with anti-infective agents (AI-CVCs).…”

Section: Introductionmentioning

confidence: 99%

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Hockenhull¹,

Dwan²,

Boland³

et al. 2008

Health Technol Assess

View full text Add to dashboard Cite

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“…In prospective randomized clinical trails, the Oligon Vantex CVCs (SPC-CVCs) significantly reduced the incidence of catheter colonization (7,36). However, the study by Ranucci et al lacked the power to detect differences in rates of catheterrelated bloodstream infection (36).…”

Section: Discussionmentioning

confidence: 99%

Comparative In Vitro Efficacies and Antimicrobial Durabilities of Novel Antimicrobial Central Venous Catheters

Hanna

Bahna

Reitzel

et al. 2006

Antimicrob Agents Chemother

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We investigated the efficacies and durability of novel antimicrobial central venous catheters (CVCs) in preventing the adherence of microbial organisms to the surfaces of the CVCs. Novel antimicrobial CVCs investigated in this in vitro study were impregnated with antibiotics (minocycline and rifampin), with Oligon agent (silver, platinum, and carbon black), with approved antiseptics (chlorhexidine and silver sulfadiazine), or with a novel antiseptic agent, gendine, which contains gentian violet and chlorhexidine. When tested against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, gendine-coated CVC segments provided protection against bacterial adherence significantly more than all other types of tested CVCs (P < 0.05). Gendine-coated CVCs also provided better protection against Candida albicans and Candida parapsilosis than CVCs impregnated with antibiotics or with silver, platinum, and carbon (P < 0.02). After 28 days of being soaked in serum, the CVCs impregnated with chlorhexidine and silver sulfadiazine and the CVCs impregnated with silver, platinum, and carbon had lost antimicrobial activity against MRSA, P. aeruginosa, and C. parapsilosis, and the CVCs impregnated with minocycline and rifampin had lost activity against P. aeruginosa and C. parapsilosis. The CVCs impregnated with gendine maintained antimicrobial activities against MRSA, P. aeruginosa, and C. parapsilosis after 28 days of being soaked in serum. Central venous catheters impregnated with the novel investigational antiseptic gendine showed in vitro efficacy and provided protection against bacterial adherence more than other approved novel antimicrobial-coated CVCs.

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“…Similar to what has been seen with ventilator care and the incidence of pneumonia, educational and behavioral campaigns can reduce these risks [81,82]. In addition, several variations of catheter design have been introduced, including silver alloy, silver iontophoretic, first-(external only) or second-(external and internal) generation chlorhexadine-silver sulfadiazine (CSS) catheters, and antibiotic-impregnated catheters [83][84][85][86][87][88][89][90][91].…”

Section: Blood Stream Infectionsmentioning

confidence: 99%

“…In multiple studies, silver alloy-coated catheters did not confer a benefit over standard catheters [83,84], and silver iontophoretic catheters produced mixed results [85,86]. Several independent trials and meta-analyses have demonstrated reduced central venous catheter colonization and CR-BSI with the use of CSS rather than uncoated catheters [87][88][89][90][91][92].…”

Section: Blood Stream Infectionsmentioning

confidence: 99%

Use of Silver in the Prevention and Treatment of Infections: Silver Review

Politano

Campbell

Rosenberger

et al. 2013

Surgical Infections

165

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Background: The use of silver for the treatment of various maladies or to prevent the transmission of infection dates back to at least 4000 b.c.e. Medical applications are documented in the literature throughout the 17th and 18th centuries. The bactericidal activity of silver is well established. Silver nitrate was used topically throughout the 1800s for the treatment of burns, ulcerations, and infected wounds, and although its use declined after World War II and the advent of antibiotics, Fox revitalized its use in the form of silver sulfadiazine in 1968. Method: Review of the pertinent English-language literature. Results: Since Fox's work, the use of topical silver to reduce bacterial burden and promote healing has been investigated in the setting of chronic wounds and ulcers, post-operative incision dressings, blood and urinary catheter designs, endotracheal tubes, orthopedic devices, vascular prostheses, and the sewing ring of prosthetic heart valves. The beneficial effects of silver in reducing or preventing infection have been seen in the topical treatment of burns and chronic wounds and in its use as a coating for many medical devices. However, silver has been unsuccessful in certain applications, such as the Silzone heart valve. In other settings, such as orthopedic hardware coatings, its benefit remains unproved. Conclusion: Silver remains a reasonable addition to the armamentarium against infection and has relatively few side effects. However, one should weigh the benefits of silver-containing products against the known side effects and the other options available for the intended purpose when selecting the most appropriate therapy.

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A prospective, randomized study in critically ill patients using the Oligon Vantex® catheter

Cited by 61 publications

References 39 publications

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Comparative In Vitro Efficacies and Antimicrobial Durabilities of Novel Antimicrobial Central Venous Catheters

Use of Silver in the Prevention and Treatment of Infections: Silver Review

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