A prospective assessment of bleeding and international normalized ratio in warfarin-anticoagulated patients having cutaneous surgery

Multiple Anticoagulant Use Increases Wound Complications Following Resection of Lower Extremity Soft Tissue Sarcomas

“…Lastly, Bordeaux et al not only discerned that ≥2 antiplatelets and anticoagulants led to increased bleeding complications in dermatologic surgeries, but also that warfarin use had a significantly higher risk of bleeding complications such as hematoma and haemorrhage [28]. This finding has been echoed in other studies evaluating post-operative complication in the cutaneous setting [28,32,33].…”

The efficacy of a hemostatic agent in anticoagulant drug-induced rat bleeding model

“…Bordeaux et al [18] supported that warfarin use significantly increased the risk of bleeding (p<0.001). In their prospective study, Syed et al [19] reported that there was more bleeding in patients on warfarin therapy when compared with the controls in cutaneous surgery. In our study, warfarin use in the control group increased the bleeding time from 1.20 minutes to 3.61 minutes and increased the amount of bleeding from 0.11 mg to 0.34; although these values were found to be highly significant, they did not cause life-threatening problems.…”

Preventing bleeding and thromboembolic complications in atrial fibrillation patients undergoing surgery

“…Simple skin biopsies should be done without any change in anticoagulant use. Excision of lesions (nevi, keratosis, carcinomas) are frequently associated with minor bleedings but rarely (< 5%) major ones, and optimization of local hemostasis should generally suffice 58,59 . Cataract extraction is an avascular surgery usually done nowadays with phacoemulsion and topical anesthetics -retrobulbar anesthesia is rarely associated with significant bleeding in anticoagulated patients but this could mandate urgent decompression 60 .…”