PLoS ONE volume 9, issue 5, Pe98368 2014 DOI: 10.1371/journal.pone.0098368 View full text
Li-rong Yan, Dong-xue Wang, Hong Liu, Xiao-xing Zhang, Hui Zhao, Lu Hua, Ping Xu, Yi-shi Li

Abstract: ObjectivesThis study aims to compare the protein composition of high-density lipoprotein (HDL) particles in coronary heart disease (CHD) patients and controls by proteomic methods.BackgroundHDL has been reported to exert pro-atherogenic properties in CHD patients. Accumulating evidence indicates that HDL composition, rather than the HDL-C level, determines its functions. The changes in HDL composition involved in the conversion of anti-atherogenic to pro-atherogenic properties in CHD patients are currently unk…

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