A preliminary study of serotonergic antidepressants in treatment of dysthymia

Dysthymic disorder: Treatment with citalopram

“…In fact, open-label and controlled trials have demonstrated efficacy of a variety of agents, useful for the treatment of major depression, for the treatment of patients with dysthymic disorder. These treatments involve tricyclic antidepressants, monoamine oxidase inhibitors, newer medications such as SSRIs, venlafaxine, mirtazapine, and psychotherapies which have been developed for the treatment of depression such as cognitive behavioral therapy, the Cognitive Behavioral Analysis System of Psychotherapy, and interpersonal psychotherapy [Kocsis et al, 1988Rosenthal et al, 1992;Harrison and Stewart, 1993;Howland, 1991;Keller et al, 1993Keller et al, , 2000Vanelle et al, 1997;Hellerstein et al, 1993Hellerstein et al, , 1999Hellerstein et al, , 2000Ravindran et al, 1994Ravindran et al, , 1998Ravindran et al, , 1999Ravindran et al, , 2000Nobler et al, 1996;Dunner et al, 1996Dunner et al, , 1997Dunner et al, , 1999Dunner, 1996Dunner, , 1998Thase et al, 1996;Markowitz, 1996;McCullough, 1991McCullough, , 2000Ballus et al, 2000;Lima and Moncrieff, 2000;Williams et al, 2000].…”

Dysthymic disorder: Treatment with citalopram

“…In fact, open-label and controlled trials have demonstrated efficacy of a variety of agents, useful for the treatment of major depression, for the treatment of patients with dysthymic disorder. These treatments involve tricyclic antidepressants, monoamine oxidase inhibitors, newer medications such as SSRIs, venlafaxine, mirtazapine, and psychotherapies which have been developed for the treatment of depression such as cognitive behavioral therapy, the Cognitive Behavioral Analysis System of Psychotherapy, and interpersonal psychotherapy [Kocsis et al, 1988Rosenthal et al, 1992;Harrison and Stewart, 1993;Howland, 1991;Keller et al, 1993Keller et al, , 2000Vanelle et al, 1997;Hellerstein et al, 1993Hellerstein et al, , 1999Hellerstein et al, , 2000Ravindran et al, 1994Ravindran et al, , 1998Ravindran et al, , 1999Ravindran et al, , 2000Nobler et al, 1996;Dunner et al, 1996Dunner et al, , 1997Dunner et al, , 1999Dunner, 1996Dunner, , 1998Thase et al, 1996;Markowitz, 1996;McCullough, 1991McCullough, , 2000Ballus et al, 2000;Lima and Moncrieff, 2000;Williams et al, 2000].…”

Major depression, minor depression, and double depression: Are they distinct clinical entities?

“…Sleep studies where reduced REM latency was examined in patients with dysthymic disorder and major depressive disorder showed more similarities than differences between groups [Akiskal et al, 1980;Haurl and Satela, 1984;Cluydts et al, 19891. dysthymia and major depression. Specifically, dysthymic patients often have an excellent response to antidepressant chemotherapy with tricyclic antidepressants and monoamine oxidase (MAO) inhibitors, as reviewed by Howland [19911. More recent work has suggested that the serotonin reuptake inhibitor fluoxetine [Rosenthal et al, 1992;Ravindran et al, 19941 is also effective in treating both dysthymia and major depression.…”

Treatment of dysthymic disorder

“…In the Rosenthal et al (1992) study, dysthymic patients were randomly assigned to treatment with fluoxetine or trazodone and were followed for five months. Assessments included the 21-item HAM-D, the SCL-58, and the patient-rated CGI (p-CGI).…”

Dysthymic disorder: Treatment with citalopram

“…In fact, open-label and controlled trials have demonstrated efficacy of a variety of agents, useful for the treatment of major depression, for the treatment of patients with dysthymic disorder. These treatments involve tricyclic antidepressants, monoamine oxidase inhibitors, newer medications such as SSRIs, venlafaxine, mirtazapine, and psychotherapies which have been developed for the treatment of depression such as cognitive behavioral therapy, the Cognitive Behavioral Analysis System of Psychotherapy, and interpersonal psychotherapy [Kocsis et al, 1988Rosenthal et al, 1992;Harrison and Stewart, 1993;Howland, 1991;Keller et al, 1993Keller et al, , 2000Vanelle et al, 1997;Hellerstein et al, 1993Hellerstein et al, , 1999Hellerstein et al, , 2000Ravindran et al, 1994Ravindran et al, , 1998Ravindran et al, , 1999Ravindran et al, , 2000Nobler et al, 1996;Dunner et al, 1996Dunner et al, , 1997Dunner et al, , 1999Dunner, 1996Dunner, , 1998Thase et al, 1996;Markowitz, 1996;McCullough, 1991McCullough, , 2000Ballus et al, 2000;Lima and Moncrieff, 2000;Williams et al, 2000].…”

Major depression, minor depression, and double depression: Are they distinct clinical entities?

“…Sleep studies where reduced REM latency was examined in patients with dysthymic disorder and major depressive disorder showed more similarities than differences between groups [Akiskal et al, 1980;Haurl and Satela, 1984;Cluydts et al, 19891. dysthymia and major depression. Specifically, dysthymic patients often have an excellent response to antidepressant chemotherapy with tricyclic antidepressants and monoamine oxidase (MAO) inhibitors, as reviewed by Howland [19911. More recent work has suggested that the serotonin reuptake inhibitor fluoxetine [Rosenthal et al, 1992;Ravindran et al, 19941 is also effective in treating both dysthymia and major depression.…”

Treatment of dysthymic disorder

“…In the Rosenthal et al (1992) study, dysthymic patients were randomly assigned to treatment with fluoxetine or trazodone and were followed for five months. Assessments included the 21-item HAM-D, the SCL-58, and the patient-rated CGI (p-CGI).…”

Dysthymic disorder: Treatment with citalopram

“…In fact, open-label and controlled trials have demonstrated efficacy of a variety of agents, useful for the treatment of major depression, for the treatment of patients with dysthymic disorder. These treatments involve tricyclic antidepressants, monoamine oxidase inhibitors, newer medications such as SSRIs, venlafaxine, mirtazapine, and psychotherapies which have been developed for the treatment of depression such as cognitive behavioral therapy, the Cognitive Behavioral Analysis System of Psychotherapy, and interpersonal psychotherapy [Kocsis et al, 1988Rosenthal et al, 1992;Harrison and Stewart, 1993;Howland, 1991;Keller et al, 1993Keller et al, , 2000Vanelle et al, 1997;Hellerstein et al, 1993Hellerstein et al, , 1999Hellerstein et al, , 2000Ravindran et al, 1994Ravindran et al, , 1998Ravindran et al, , 1999Ravindran et al, , 2000Nobler et al, 1996;Dunner et al, 1996Dunner et al, , 1997Dunner et al, , 1999Dunner, 1996Dunner, , 1998Thase et al, 1996;Markowitz, 1996;McCullough, 1991McCullough, , 2000Ballus et al, 2000;Lima and Moncrieff, 2000;Williams et al, 2000].…”

Major depression, minor depression, and double depression: Are they distinct clinical entities?

“…Sleep studies where reduced REM latency was examined in patients with dysthymic disorder and major depressive disorder showed more similarities than differences between groups [Akiskal et al, 1980;Haurl and Satela, 1984;Cluydts et al, 19891. dysthymia and major depression. Specifically, dysthymic patients often have an excellent response to antidepressant chemotherapy with tricyclic antidepressants and monoamine oxidase (MAO) inhibitors, as reviewed by Howland [19911. More recent work has suggested that the serotonin reuptake inhibitor fluoxetine [Rosenthal et al, 1992;Ravindran et al, 19941 is also effective in treating both dysthymia and major depression.…”

Treatment of dysthymic disorder

“…In the Rosenthal et al (1992) study, dysthymic patients were randomly assigned to treatment with fluoxetine or trazodone and were followed for five months. Assessments included the 21-item HAM-D, the SCL-58, and the patient-rated CGI (p-CGI).…”