A population-based study of Coats disease in the United Kingdom I: epidemiology and clinical features at diagnosis

Morris, Bishoy; Foot, B; Mulvihill, Alan

doi:10.1038/eye.2010.126

Cited by 67 publications

(64 citation statements)

References 14 publications

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“…younger than that of previous reports [2][3][4]16 and thus potentially of greater risk of treatment failure secondary to severe inflammation. Furthermore, the extended median follow-up of more than 4 years revealed the occurrence of late complications such as cataract, tractional vitreoretinopathy, and phthisis bulbi.…”

Section: Discussioncontrasting

confidence: 56%

“…2 It is typically unilateral, affecting young males (85%) more than females (15%) with a median age of 8 years. [2][3][4] Coats disease is characterized by peripheral retinal telangiectasia with secondary intraretinal and subretinal exudates, exudative retinal detachment, and ischemic peripheral retinopathy that can lead to iris neovascularization and neovascular glaucoma. Several classifications of Coats disease have been put forward, based on severity and anatomical/functional prognosis.…”

mentioning

confidence: 99%

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Ranibizumab in the Management of Advanced Coats Disease Stages 3b and 4

Gaillard

Mataftsi

Balmer

et al. 2014

Retina

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To the best of the authors' knowledge, this is the largest reported series of late-stage Coats undergoing anti-vascular endothelial growth factor therapy, a homogenous cohort of patients treated with a single agent and with the longest follow-up. This study supports the role of ranibizumab in advanced disease by transient restoration of the hemato-retinal barrier and suppression of neovascularization to facilitate classic treatment. At the last follow-up, the authors report unprecedented anatomical success and functional outcome.

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Section: Discussioncontrasting

confidence: 56%

mentioning

confidence: 99%

Ranibizumab in the Management of Advanced Coats Disease Stages 3b and 4

Gaillard

Mataftsi

Balmer

et al. 2014

Retina

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“…It also may be found as an incidental finding during a routine ocular examination. 4 Untreated Coats' disease may cause vision loss resulting from macular involvement, and in advanced disease, there may be exudative retinal detachment with secondary neovascular glaucoma. 5, 6 Shields et al 7 classified Coats' disease into different stages (Table 1).…”

mentioning

confidence: 99%

“…3 Coats' disease is rare, with a reported incidence of 0.09 per 100 000 of the population. 4 It usually manifests in childhood with leukocoria, strabismus, or reduced acuity often detected during vision screening. It also may be found as an incidental finding during a routine ocular examination.…”

mentioning

confidence: 99%

Intraoperative Fluorescein Angiography–Guided Treatment in Children with Early Coats' Disease

Suzani

Moore

2015

Ophthalmology

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“…Visual prognosis in advanced Coats disease is generally poor,5 and if not treated can lead to a blind painful eye secondary to neovascular glaucoma but early cases can respond very well to treatment with good visual outcomes 6. The mainstay of treatment is cryotherapy and laser to the abnormal retinal vessels to limit exudation.…”

Section: Discussionmentioning

confidence: 99%