A point prevalence surveillance study from pediatric and neonatal specialty hospitals in India

Singh, Sanjeev; Jose, Tency; Versporten, Ann; Sengupta, Shamik; Fini, P.; Sharland, Mike; Kumar, Raman Krishna; Goossens, Herman

doi:10.3233/jpi-140429

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…In our study, a significant portion of antibiotics was mostly used for the treatment of community-acquired infections (62.6%), and these results are similar to studies in Nigeria and Sweden and to two other studies conducted in India, which reports community acquired infections (CAI) as an indication with the highest prevalence of antimicrobial use 7,12 . The clinical sign documented for the treatment with antimicrobials is vital to evaluate compliance with national antimicrobial treatment guide lines (ICMR Guidelines).…”

Section: Discussionsupporting

confidence: 89%

A Point Prevalence Survey Of Antimicrobial Prescribing In A South Indian Tertiary Hospital; Using Global PPS Tool

Chadalavada

Babu²,

Balamurugan

2021

Asian Journal of Pharmaceutical Research and Health Care

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Identifying the targets for improving antimicrobial prescription and development of antimicrobial stewardship interventions can better serve to combat the situation of antimicrobial resistance. The primary objective was to determine the prevalence of antimicrobial use at tertiary care teaching hospital with both acute and long-term care patients. A periodical point prevalence survey was done in a tertiary care hospital of South India during 2019 using manual and webbased GLOBAL-PPS tool. Of 945 patients eligible for the study, 645 (69.5 %) received at least one antibiotic, with highest rates in the adult surgical ward and pediatrics. Of 645 therapeutic antibiotic prescriptions, 58.6% prescriptions have an infectious indication of them, 62.6% are community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. The prevalence of antibiotic use is very high, and our study evidence that the country needs a robust antimicrobial stewardship intervention program.

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Section: Discussionsupporting

confidence: 89%

A Point Prevalence Survey Of Antimicrobial Prescribing In A South Indian Tertiary Hospital; Using Global PPS Tool

Chadalavada

Babu²,

Balamurugan

2021

Asian Journal of Pharmaceutical Research and Health Care

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“…AU : Anabbreviationlisthasbeencompiledforthoseusedinthetext:Pleaseverifythatallentriesarecorrect: Hospital-associated infections (HAIs) are a common cause of morbidity and mortality [1], in particular among vulnerable patients [2]. Many HAIs caused by common bacterial pathogens are no longer treatable with affordable first-line antibiotics, such as penicillins and cephalosporins [3,4].…”

Section: Introductionmentioning

confidence: 99%

Global incidence in hospital-associated infections resistant to antibiotics: An analysis of point prevalence surveys from 99 countries

Balasubramanian¹,

Boeckel

Carmeli

et al. 2023

PLoS Med

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Background Hospital-associated infections (HAIs) are an important cause of morbidity and mortality around the world. Many HAIs are caused by drug-resistant bacterial pathogens, but there are major gaps in our understanding of the number of hospital-associated drug-resistant infections (HARIs) worldwide. As such, we estimated trends in prevalence of HARIs caused by high priority pathogens (Escherichia coli, Acinetobacter spp., Klebsiella spp., Staphylococcus aureus, Enterobacter spp., and Pseudomonas spp.) in 195 countries. Methods and findings Resistance prevalence estimates were extracted from 474-point prevalence surveys (PPS) from 99 countries published between 2010 and 2020 coupled with country-level estimates of hospitalization rates and length of stay. Prevalence estimates were transformed in yearly incidence of HARIs per year by country and income group. We estimate the global number of HARIs per year to be 136 million (95% credible interval (CI) 26 to 246 million) per year, with the highest burden in China (52 million, 95% CI 10 to 95 million), Pakistan (10 million, 95% CI 2 to 18 million), and India (9 million, 95% CI 3 to 15 million). Among income groups, middle-income countries bore the highest burden of HARIs per year (119 million, 95% CI 23 to 215 million). Our analysis was constrained by the limited number of PPS for HARIs, lack of community-associated data on antibiotic-resistant infections, and our population level analysis. Conclusions In this study, we observe, in the absence of systematic surveillance systems for HARIs, a baseline overview of their rates. Our yearly estimates highlight the global threat of HARIs and may help define strategies to tackle resistance in hospital settings.

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Study to assess quality of antimicrobial use by point prevalence survey at a tertiary care centre

Vadivoo¹,

Уша²,

Sudha³

2019

IJMR

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Knowledge and perception of rational Antimicrobial Use (AU) help in developing interventions to improve AU. Data to target AU surveillance and interventions are provided by Point Prevalence surveys, which are a resource-effective alternative to prospective surveillance. Point Prevalence Survey (PPS) on AU provides a snapshot of antibiotic use at a given point of time and can be repeated at regular intervals to monitor trends. It provides data that can be fed back to front line clinicians and used to inform discussions about stewardship. In Our 670 bedded tertiary care Hospital, we did the PPS during last week of Jan 2019 in the identified wards and ICU's. A survey team reviewed patients' case sheet and noted antibiotics prescriptions on the date of the survey. Other important details such as admitting ward, age, sex, total number of patients on admissions, administered antibiotics and its route, their dosages, dosing intervals, patients' clinical diagnosis and indications for antibiotic use, Hospital-acquired infections (HAI) or Communityacquired (CAI) and surgical antibiotic prophylaxis (SAP) or Medical antibiotics prophylaxis(MAP). Of 502 patients admitted in the hospital, 325(64.7%) received ≥1 Antimicrobial orders (AO) on the date of the survey. Of 325 total AOs, 98 (30.2 %) were administered for (SAP) surgical prophylaxis, 19(5.84%) for Medical prophylaxis, (MAP), 23(7%) for reasons not documented in the medical record, i.e., Unknown-(UK), 167 (51.38%) were for CAI and 18(5.3%) for HAI. Parenteral Cefotaxim was the most prevalent antibiotic generally used and for all types of infection onset category.51% of all prescriptions for CAI was for respiratory infections. Broad spectrum AO treatment was prevalent, for both SAP and CAI infections. Understanding common reasons for Antibiotic use (e.g., Lower respiratory infection) can help focus education and stewardship efforts on areas in which improved use may have the greatest impact.

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A point prevalence surveillance study from pediatric and neonatal specialty hospitals in India

Cited by 3 publications

References 5 publications

A Point Prevalence Survey Of Antimicrobial Prescribing In A South Indian Tertiary Hospital; Using Global PPS Tool

A Point Prevalence Survey Of Antimicrobial Prescribing In A South Indian Tertiary Hospital; Using Global PPS Tool

Global incidence in hospital-associated infections resistant to antibiotics: An analysis of point prevalence surveys from 99 countries

Study to assess quality of antimicrobial use by point prevalence survey at a tertiary care centre

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