A photoacoustic FTIRS study of the chemical modifications of human dentin surfaces:

Effects of 980 nm diode laser application protocols on the reduction of Enterococcus faecalis intracanal biofilm: An in vitro study

“…However, improper application may lead to very harmful side effects. Sodium hypochlorite is very cytotoxic when inadvertently injected to periapical tissues, 11 since it promotes dentine deproteination 12 and adversely affects bond strength of adhesive material to dentine tissue. 13 In rare cases of NaOCl allergy, 14,15 the use of this substance is contraindicated.…”

Effect of different acidities of electrolyzed water on dentin surface roughness, decalcification and microhardness —a preliminary study

“…Di Renzo et al noted that 12% NaOCl is most effective at dissolving the organic matter in dentin during the initial 2 min, and that this dissolution effect is discontinued after 15 min 21) . In the present study, the microhardness of the NL group revealed a higher decreasing trend than that of the DW group after 60 min; however, there was no significant difference between these two groups except 60 min immersion.…”

Effectiveness of high-power diode laser associated to chemical auxiliary substance on decontamination of root canal system infected with Enterococcus faecalis – an in vitro study

“…This substance has effective antimicrobial activity 23 and ability to dissolve organic tissues 30 . However, is extremely cytotoxic when extravasated to the periapical tissues 31 , promotes dentin deproteination 32 and interferes negatively on bond strength between restorative material and dentin 33 . Chlorhexidine has been used as an alternative to chemical auxiliary substance in the root canal preparation its broad antimicrobial spectrum 26 and substantivity 34 .…”