A phase III single-arm study of a new 13.5 mg levonorgestrel intrauterine contraceptive system in postmenarcheal adolescents: an evaluation of efficacy, bleeding, user satisfaction, and placement

Gemzell‐Danielsson, Kristina; Dermout, Sylvia; Lukkari-Lax, Eeva; Montegriffo, Elaine; Rybowski, Sarah; Apter, Dan

doi:10.1016/j.fertnstert.2014.07.484

Cited by 4 publications

(3 citation statements)

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“…IUS12 was associated with high levels of user satisfaction, with more than 80% of women completing the study. Insertions were rated by investigators as 'easy' in 94.4% of cases, and most women (> 50%) reported no more than 'mild' pain during insertion (48).…”

Section: Ius12 In Adolescentsmentioning

confidence: 99%

The new LNG-releasing IUS: a new opportunity to reduce the burden of unintended pregnancy

Cristóbal¹,

Neyro²,

Lete³

2015

European Journal of Obstetrics & Gynecology and Reproductiv

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Unintended pregnancies still remain a worldwide public health problem. They have received much attention in adolescents given the strong impact they have on their present and future lives. Young women wishing to delay maternity are also especially vulnerable to unintended pregnancies. Studies have revealed a pattern of use of contraceptive methods that is likely to increase this risk. Methods of long-acting reversible contraception (LARC), among which copper and levonorgestrel-releasing intrauterine devices (IUD and IUS) are the most common, have been widely recommended to avoid unintended pregnancy at any age. Despite this, the use of these devices is very limited. Several barriers to their wide spread use have been identified, which specially affect a higher use by nulliparous women. A new levonorgestrel-releasing IUS containing only 13.5mg of levonorgestrel (IUS12) recently marketed as Jaydess® in Europe, has a smaller size, provides a shorter duration of action, and a lower hormonal content compared to Mirena®, along with a similar efficacy and safety profile, may offer a long-term option that better addresses the needs of nulliparous women. Evidence on the risk of unintended pregnancies in young women--with a special emphasis in Europe, barriers associated with a lower-than-desirable use of LARC methods--especially intrauterine devices (IUD and IUS), and the potential benefits of the new IUS12 including changes in bleeding pattern, safety and user satisfaction--especially with respect to nulliparous and adolescents--are reviewed here. Evidence supports that IUS12 may offer a LARC option that better addresses the needs of these women.

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Section: Ius12 In Adolescentsmentioning

confidence: 99%

The new LNG-releasing IUS: a new opportunity to reduce the burden of unintended pregnancy

Cristóbal¹,

Neyro²,

Lete³

2015

European Journal of Obstetrics & Gynecology and Reproductiv

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“…Only 10.9% reported that the procedure was very painful. This study also revealed a high level of satisfaction with the chosen method of contraception; 83.9% of the subjects were satisfied or very satisfied with the levonorgestrel-based intrauterine device 8 .…”

Section: Discussionmentioning

confidence: 62%

“…Lediglich 10,9% gaben an, die Einlage als sehr schmerzhaft empfunden zu haben. Auch in dieser Studie zeigte sich eine hohe Zufriedenheit mit der angewandten Form der Kontrazeption, 83,9% der Probandinnen waren zufrieden oder sehr zufrieden mit dem levonorgestrelhaltigen Intrauterinsystem 8 .…”

Section: Diskussionunclassified

Situation of Adolescent Contraceptive Use in Germany

Oppelt

Fahlbusch

Heusinger

et al. 2018

Geburtshilfe Frauenheilkd

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Introduction Would adolescent girls in Germany choose a different method of contraception to the combined oral contraceptive if provided with the appropriate information? Is there a need for long-acting contraception among our adolescent girls? How satisfied are female patients with the information they receive at their respective gynaecology practices, and how much do the girls know about different methods of contraception? Materials and Methods In the study “Thinking About Needs in COntraception” (TANCO), not only female patients, but also their respective gynaecologists were surveyed online about current methods of contraception, their satisfaction with these methods, and also their level of knowledge concerning the individual methods of contraception, the situation related to advice about different contraceptive options and their general satisfaction with gynaecological care. This article presents the data from the subset of adolescent girls aged 14 to 19 years (n = 2699) out of the total of 18 521 women surveyed. Results The girls surveyed were familiar with at least the name of more than five different methods of contraception (average 5.3). The doctors assumed that the respondents would know only 4.2 different methods. When asked explicitly about how the individual methods of contraception work, clear deficits became evident. This applies not only to the entire population of respondents, but also the users of the respective contraceptive method. In addition, a strong interest in long-acting contraception emerged from the survey, particularly among young women. Discussion The data from the TANCO study reveal a clear discrepancy between the existing contraception almost exclusively in the form of the contraceptive pill and the contraceptive options considered by adolescent girls if they are thoroughly informed. The need for education into alternatives to the pill is high, as is the willingness to use such alternatives after receiving information – much higher than the figures suggested by the gynaecologists.

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Kombinierte Kontrazeption sollte Standard sein

Baier

2017

Pädiatrie

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A phase III single-arm study of a new 13.5 mg levonorgestrel intrauterine contraceptive system in postmenarcheal adolescents: an evaluation of efficacy, bleeding, user satisfaction, and placement

Cited by 4 publications

References 0 publications

The new LNG-releasing IUS: a new opportunity to reduce the burden of unintended pregnancy

The new LNG-releasing IUS: a new opportunity to reduce the burden of unintended pregnancy

Situation of Adolescent Contraceptive Use in Germany

Kombinierte Kontrazeption sollte Standard sein

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