volume 10, issue 6, P1366-1379 2018
DOI: 10.18632/aging.101473
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Jin Zhang, Lixiao Yang, Xiaohong Xiang, Zhuoying Li, Kai Qu, Ke Li

Abstract: Ovarian cancer yields the highest mortality rate of all lethal gynecologic cancers, and the prognosis is unsatisfactory with the major obstacle in resistance to chemotherapy. The generation of reactive oxygen species (ROS) in tumor tissues was associated with chemotherapeutic effectiveness by mediating cellular longevity. In this study, we screened the prognostic values of oxidative stress-related genes in ovarian cancer patients received platinum-based chemotherapy, and conducted a prognostic gene signature c…

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