2002
DOI: 10.5012/bkcs.2002.23.3.374
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Abstract: Several compounds of 3,9-dialkylxanthines were prepared from 1-methyl-6-chlorouracil via nucleophillic reactions with different aliphatic amines, followed by nitrosation, reduction, formaylation and finally dehydrocyclization. On the other hands, a series of 8-aryl-3,9-dimethylxanthines were synthesized by dehydrocyclization of 5-arylamido-1-methyl-6-methylaminouracils either by fussion or oxidation of 5-arylidineamino-1-methyl-6-methylaminouracils using sodium periodate. Phosphoryl chloride was found to be un… Show more

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