2019
DOI: 10.2217/bmm-2019-0036
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A Novel Nomogram for the Differential Diagnosis Between Advanced and Early Appendicitis in Pediatric Patients

Abstract: Aim: To develop a nomogram for differential diagnosis between advanced and early pediatric appendicitis (PA). Patients & methods: We retrospectively studied 669 PA patients. Patient characteristics and 24 serum markers were subjected to univariate and multivariate analysis, based on which the nomogram was constructed. Results: Fibrin degradation product, CRP and Na+ differed significantly between the advanced and early PA. The value of area under the receiver operating characteristic curve (AUC) was 0.8602… Show more

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Cited by 3 publications
(2 citation statements)
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“…A pivot consisting of pain, inflammatory changes, and anorexia might be found in other conditions mimicking AA, such as mesenteric adenitis, Crohn's ileitis, infections with Yersinia or Campylobacter, torsion of epiploic appendages, or tubo-ovarian abscesses [42]. Very few of these conditions require urgent intervention, with some even being exacerbated by surgery [43]. This underscores the value of radiological signs when establishing a definitive diagnosis.…”
Section: Acute Appendicitismentioning
confidence: 99%
“…A pivot consisting of pain, inflammatory changes, and anorexia might be found in other conditions mimicking AA, such as mesenteric adenitis, Crohn's ileitis, infections with Yersinia or Campylobacter, torsion of epiploic appendages, or tubo-ovarian abscesses [42]. Very few of these conditions require urgent intervention, with some even being exacerbated by surgery [43]. This underscores the value of radiological signs when establishing a definitive diagnosis.…”
Section: Acute Appendicitismentioning
confidence: 99%
“…The differential diagnosis includes Crohn disease, ruptured ovarian cyst, ovarian torsion, round ligament syndrome, salpingitis, mittelschmerz, ectopic pregnancy, tubo-ovarian abscess, endometriosis, pelvic inflammatory disease, gastroenteritis, right-sided colitis, renal colic, kidney stones, testicular torsion, and other nondescript gastroenterological issues [4].…”
Section: Introductionmentioning
confidence: 99%