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Cited by 11 publications
(8 citation statements)
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References 19 publications
(41 reference statements)
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“…35 Indeed, our preliminary study 14 and others 12,36 have shown that the induction phase is a critical time for hematological cancer treatment with more impact on oral physiological parameters such as saliva, oral microbiota, and host cell interactions. Although some previous studies have also evaluated these response variables (USF and oral streptococci load), the results are crosssectional 11,13,18 or longitudinal of short-term periods (50 days for the endpoint), 9,22,37,38 which are not able to completely evaluate the impact of cancer therapy on different follow-up time-points.…”
Section: Discussionmentioning
confidence: 99%
“…8,9 This cancer treatment can particularly induce some physicochemical changes in the saliva characteristics, such as the excretion flow rate, organic and inorganic composition, and immunological properties. 10,11 Salivary changes in children have consequently been associated with deteriorating oral health status during chemotherapy. 9,[12][13][14] However, some cross-sectional studies 15,16 have shown controversial results regarding chemotherapy's effect on the salivary flow rate because the saliva exams were performed in different early stages of cancer treatment.…”
Section: Introductionmentioning
confidence: 99%
“…Advanced cases, in contrast, commonly require chemotherapy and/or surgery. 1,2 The deleterious effects of radiation on bone tissue have been closely examined with the goal of elucidating the mechanisms leading to osteoradionecrosis, 3 but conclusive evidence is not yet available. Histomorphometric analysis of biopsies has proven to be a valuable laboratory method to evaluate bone quality, while clinical methods include digital radiography, ultrasonography, and computed tomography.…”
Section: Introductionmentioning
confidence: 99%
“…A literatura afirma que a escolha do tratamento do CCP depende de sua localização e estádio (GALBIATTI et al, 2013;DEMIAN et al, 2014;VINES et al, 2017). A radioterapia é considerada a modalidade padrão para os cânceres em estádio inicial, nos casos mais avançados, é indicada a associação com cirurgia e/ou quimioterapia (PALMA et al, 2017 (GULLIFORD et al, 2012;XIAO et al, 2016;WEBER;O'BRIEN, 2016;HASHEMI et al, 2017;LIPSETT et al, 2017). Sawada et al (2012) KOMURCU, 2010;KWEKKEBOOM et al, 2012;FINNEGAN-JOHN et al, 2013;BAR-SELA et al, 2015).…”
Section: Qualidade De Vida Relacionada à Saúdeunclassified
“…Para a maioria dos cânceres de cabeça e pescoço em fase inicial, a radioterapia é considerada como a modalidade terapêutica padrão, seu principal objetivo é controlar a evolução do tumor com o menor dano possível aos tecidos e órgãos normais adjacentes (PALMA et al, 2017). O tratamento radioterápico apesar de apresentar a vantagem de preservar a estrutura dos tecidos, pode acarretar reações adversas que se manifestam na cavidade oral, entre elas estão a mucosite,…”
Section: Introductionunclassified