A novel intra-tumoral drug delivery carrier for treatment of oral squamous cell carcinoma
Shimaa A. Elsaady,
Moustafa N. Aboushelib,
Essam Al-Wakeel
et al.
Abstract:The treatment of oral squamous cell carcinoma (OSCC) includes systemic chemotherapy and is associated with aggressive side effects on patients. This study evaluated a new intra-tumor-targeted drug delivery method for the treatment of OSCC induced on the dorsum of the tongue in white mice. The induced tumors were examined by needle biopsy. A targeted anticancer drug (Cetuximab) and [Cisplatin and 5 Fluorouracil (5-FU)] chemotherapeutic agents were loaded on polyethylene glycol-polylactide-polyethylene glycol (P… Show more
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