A Novel Imaging Technique to Measure Capillary-Refill Time: Improving Diagnostic Accuracy for Dehydration in Young Children With Gastroenteritis

Shavit, Itai; Brant, Rollin; Nijssen–Jordan, Cheri; Galbraith, Roger; Johnson, David W.

doi:10.1542/peds.2006-1108

Cited by 56 publications

(38 citation statements)

References 12 publications

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“…Poor peripheral circulation was noted in six studies, with a LR+ ranging from 2.39 to 38.8. 11,29,50,68,69,72 There did not appear to be a clear relationship between the prevalence of infection in the study setting and LR+. Rapid breathing and shortness of breath provided greatest LR+ in the single low-prevalence study, 11 with a LR+ of 9.3-9.7.…”

Section: Circulatory and Respiratory Clinical Featuresmentioning

confidence: 80%

“…Three studies used an outcome of meningitis, [70][71][72] of which two included children with first episode of fever and seizures, 70,71 and one based on signs of meningeal irritation. 72 Two studies used an outcome of gastroenteritis causing dehydration, 68,69 one of which included children with clinical gastroenteritis 68 and the other children with diarrhoea with or without vomiting and evidence of dehydration. 69 Two studies used an outcome of pneumonia, 73,74 and included febrile children and children with clinical signs of respiratory infection.…”

Section: Outcomes Reportedmentioning

confidence: 99%

“…72 Two studies used an outcome of gastroenteritis causing dehydration, 68,69 one of which included children with clinical gastroenteritis 68 and the other children with diarrhoea with or without vomiting and evidence of dehydration. 69 Two studies used an outcome of pneumonia, 73,74 and included febrile children and children with clinical signs of respiratory infection. Finally, two studies 75,76 used meningococcal infection as an outcome, both of which included haemorrhagic or non-blanching rash as inclusion criteria.…”

Section: Outcomes Reportedmentioning

confidence: 99%

“…11 Overall assessment of severity based on clinical impression or the child appearing ill from six further studies 50,56,63,67,69,76 (all but one in intermediate-prevalence setting) provided weaker LRs+ and LRs-.…”

Section: Global Assessmentmentioning

confidence: 99%

See 3 more Smart Citations

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Thompson

Bruel²,

Verbakel³

et al. 2012

Health Technol Assess

239

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume.How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service' . The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projec...

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Section: Circulatory and Respiratory Clinical Featuresmentioning

confidence: 80%

Section: Outcomes Reportedmentioning

confidence: 99%

Section: Outcomes Reportedmentioning

confidence: 99%

Section: Global Assessmentmentioning

confidence: 99%

See 2 more Smart Citations

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Thompson

Bruel²,

Verbakel³

et al. 2012

Health Technol Assess

239

View full text Add to dashboard Cite

show abstract

“…Other methods quantifying skin reaction after blanching pressure are available [19][20][21]32], some of which have been used previously in similar applications [23,26,33,34]. The advantage of TiVi is its correlation with RBC concentration whereas other devices focus more on the general colour change of skin, possibly making data more sensitive to each subjects skin colour.…”

Section: Limitationsmentioning

confidence: 99%

Reflectance spectroscopy: to shed new light on the capillary refill test

John

Henricson

Nilsson³

et al. 2017

Journal of Biophotonics

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To use Bioengineering methodology is used to achieve, at five anatomical sites, a detailed, quantitative assessment of the return of blood content to the blanched area, during the Capillary Refill (CR) test. An observational, non-randomized, experimental study on 23 healthy subjects (14 females) was performed in our climate controlled skin physiology laboratory. Our main outcome measures were based on the chronological assessment and quantification of red blood cell concentration (RBC) after the release of blanching pressure in the CR test, using Tissue Viability Imaging (TiVi), a digital photographic technique based on polarisation spectroscopy. TiVi enabled collection of detailed data on skin RBC concentration during the CR test. The results were shown as curves with skin blood concentration (TiVi-value) on the y-axis and the time on the x-axis. Quantitative CR responses showed site and temperature variability. We also suggest possible objective endpoint values from the capillary refill curve. Detailed data on skin RBC concentration during the CR test is easily obtained and allows objective determination of end points not possible to achieve by naked eye assessment. These findings have the potential to place the utility of the CR test in a clinical setting in a new light.

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Skin‐color‐independent robust assessment of capillary refill time

Souza

Dias

Cardoso

2023

Journal of Biophotonics

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Capillary Refill Time (CRT) assesses peripheral perfusion in resource‐limited settings. However, the repeatability and reproducibility of CRT measurements are limited for individuals with darker skin. This paper presents quantitative CRT measurements demonstrating good performance and repeatability across all Fitzpatrick skin phototypes. The study involved 22 volunteers and utilized controlled compression at 7 kPa, an RGB video camera, and cocircular polarized white LED light. CRT was determined by calculating the time constant of an exponential regression applied to the mean pixel intensity of the green (G) channel. An adaptive algorithm identifies the optimal regression region for noise reduction, and flags inappropriate readings. The results indicate that 80% of the CRT readings fell within a 20% range of the expected CRT value. The repetition standard deviation was 17%. These findings suggest the potential for developing reliable and reproducible quantitative CRT methods for robust measurements in patient triage, monitoring, and telehealth applications.

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A Novel Imaging Technique to Measure Capillary-Refill Time: Improving Diagnostic Accuracy for Dehydration in Young Children With Gastroenteritis

Abstract: Results of this prospective cohort study suggest that digitally measured capillary-refill time more accurately predicts significant dehydration (> or = 5%) in young children with gastroenteritis than overall clinical assessment.

Cited by 56 publications

References 12 publications

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Reflectance spectroscopy: to shed new light on the capillary refill test

Skin‐color‐independent robust assessment of capillary refill time

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