2019
DOI: 10.1039/c9ob01407a
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A novel chemiluminescent probe for hydrazine detection in water and HeLa cells

Abstract: A novel chemiluminescent probe based on intramolecular cyclization for hydrazine detection in living cells.

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Cited by 42 publications
(11 citation statements)
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“…Thus, DX was prepared following literature procedures (see Supporting Information). , Compound DX is long-term stable for at least 1 h in acidic aqueous solutions (pH 6.0; Figure S1a) but undergoes chemical transformation and displays a blue CL emission when the pH is increased to 9.6 ( λ em,max = 471 nm, Figure S1b–d). This base-triggered CL takes place after deprotonation of the phenol moiety (p K a ≈ 9.0) of DX, leading to the formation of an electronically excited phenoxy methyl ester intermediate, E* (Figure S1e).…”
Section: Resultsmentioning
confidence: 99%
“…Thus, DX was prepared following literature procedures (see Supporting Information). , Compound DX is long-term stable for at least 1 h in acidic aqueous solutions (pH 6.0; Figure S1a) but undergoes chemical transformation and displays a blue CL emission when the pH is increased to 9.6 ( λ em,max = 471 nm, Figure S1b–d). This base-triggered CL takes place after deprotonation of the phenol moiety (p K a ≈ 9.0) of DX, leading to the formation of an electronically excited phenoxy methyl ester intermediate, E* (Figure S1e).…”
Section: Resultsmentioning
confidence: 99%
“…Several analytical methods, such as chromatography [ 15 ], fluorescence methods [ 16 ], chemiluminescence [ 17 ], and electrochemical methods [ 18 ], have been used for the detection of hydrazine in various types of samples. Among these methods, electrochemical techniques are considered to be the best because of their simplicity, low-cost fabrication process, and fast detection response, and because they possess a relatively high sensitivity and selectivity [ 19 , 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
“…[10][11][12][13][14] So far, a number of fluorescent probes have been developed to determine N 2 H 4 or viscosity, separately. [15][16][17][18][19][20][21][22][23] However, the scenario of putting these single detector probes together to gain multi-signal monitoring of N 2 H 4 and viscosity is greatly limited owing to uneven distributions, long testing time, high testing costs, and so on. In the past few years, numerous welldesigned dual-functional fluorescent probes for simultaneously analyzing multi-analytes have been developed.…”
Section: Introductionmentioning
confidence: 99%