Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2007
2007
2014
2014

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 11 publications
(2 citation statements)
references
References 29 publications
0
2
0
Order By: Relevance
“…However, it is important to note that a cyclopropyl group blocks hydride transfer, as cyclopropylidene imines are very strained, and facilitates electron transfer, as cyclopropyl groups greatly stabilize adjacent positive charge. Less strained cyclic substrates and inhibitors have failed to give the ring-opening products ( ). With the latter compounds, the lack of the ring-opening product is consistent with a nonradical mechanism.…”
Section: Discussionmentioning
confidence: 99%
“…However, it is important to note that a cyclopropyl group blocks hydride transfer, as cyclopropylidene imines are very strained, and facilitates electron transfer, as cyclopropyl groups greatly stabilize adjacent positive charge. Less strained cyclic substrates and inhibitors have failed to give the ring-opening products ( ). With the latter compounds, the lack of the ring-opening product is consistent with a nonradical mechanism.…”
Section: Discussionmentioning
confidence: 99%
“…1), a metabolite of melatonin, 15 is a substrate for both MAO-A and B and used in in vitro MAO assays. 16 The substrate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) 17 is converted into a neurotoxin by MAO-B 18 and has been explored as a scaffold for the synthesis of other MAO-substrates including 1-methyl-3-phenyl-2,5-dihydro-1Hpyrrole, 19,20 2-methylisoindolines, 19 4-(1-methyl-1H-pyrrol-2-yl)-1-(prop-2-yn-1-yl)piperidine, 21 3,4-cyclopropyl analogs of MPTP 22 as well as 1-methyl-3-phenylpyrrolidine and the 3,4-cyclopropyl analogs hereof 23 (Fig. 1).…”
Section: Introductionmentioning
confidence: 99%