A novel 1,2,4-triazole-based copper(II) complex: Synthesis, characterization, magnetic property and nuclease activity

Interaction of copper(II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: Synthesis, structure, DNA- and albumin-binding

“…The viscosity of a DNA solution has been measured in the presence of increasing amounts of ligands or complexes 1-7. The relation between the relative solution viscosity (η/η 0 ) and DNA length (L/L 0 ) is given by the equation L/L 0 = (η/η 0 ) 1/3 , where L 0 denotes the apparent molecular length in the absence of the compound [67]. The obtained data are presented as (η/ η 0 ) 1/3 versus r, where η is the viscosity of DNA in the presence of complex, and η 0 is the viscosity of DNA alone in buffer solution.…”

“…DNA viscosity is sensitive to DNA length change; therefore, its measurement upon addition of a compound is often concerned as the least ambiguous method to clarify the interaction mode of a compound with DNA and provides reliable evidence for the intercalative binding mode [47,67,[82][83][84]. In the case of classic intercalation, DNA base pairs are separated in order to host the bound compound resulting in the lengthening of the DNA helix and subsequently increased DNA viscosity.…”

Nickel–quinolones interaction. Part 4 — Structure and biological evaluation of nickel(II)–enrofloxacin complexes compared to zinc(II) analogues

“…The viscosity of a DNA solution has been measured in the presence of increasing amounts of Herx or complexes 1234. The relation between the relative solution viscosity (η/η 0 ) and DNA length (L/L 0 ) is given by the equation L/L 0 = (η/η 0 ) 1/3 , where L 0 denotes the apparent molecular length in the absence of the compound [52]. The obtained data are presented as (η/η 0 ) 1/3 versus r, where η is the viscosity of DNA in the presence of complex, and η 0 is the viscosity of DNA alone in buffer solution.…”

“…DNA viscosity is sensitive to DNA length change; therefore, its measurement upon addition of a compound is often concerned as the least ambiguous method to clarify the interaction mode of a compound with DNA and provides reliable evidence for the intercalative binding mode [52,[78][79][80][81]. In the case of classic intercalation, DNA base pairs are separated in order to host the bound compound resulting in the lengthening of the DNA helix and subsequently increased DNA viscosity.…”

Current Developments in the Syntheses of 1,2,4-Triazole Compounds

“…This transformation is highly affected by the temperature, pH and complicated operations, and only exhibits narrow application scope, but it can provide rare triazole selenium herbicides and much effort should be dedicated to this strategy to optimize the harsh reaction conditions. Additionally, the modification of functional groups which are far from triazole ring has been reported vastly due to the easily coupling reactions, and numerous 1,2,4-triazole-based supramolecular aggregates have been prepared with special properties and biological activities, and display a wide range of potential application as cation and anion artificial receptors [330][331][332][333][334][335], luminescent [336][337][338][339][340] and magnetic [341][342][343][344] materials as well as medicinal agents [3,[30][31][32].…”