A NIR fluorescent probe for rapid turn-on detection and bioimaging of hypochlorite anion

A Near-Infrared Fluorescent Probe for Recognition of Hypochlorite Anions Based on Dicyanoisophorone Skeleton

“…In connection with our previous work [ 26 , 48 , 49 ], herein, we reported a novel chemodosimeter ( SWJT-9 ), which had a large Stokes shift and emitted near-infrared fluorescence due to using a dicyanoisophorone skeleton. It can specifically recognize a hypochlorite anion based on the inhibition of C=N rotational isomerization [ 50 ].…”

“…In addition, the fluorescence probing method was paid more attention as an excellent detection tool, which has realized the detection of many active species [ 19 , 20 , 21 , 22 , 23 ]. Fluorescence probes for the detection of hypochlorite anions have been reported continuously in recent years [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. Among them, some chemodosimeters using a diaminomaleonitrile group as the reaction site were used to detect hypochlorite anions, which had many advantages, such as specific recognition, high selectivity, and fast response.…”

A dual-mode probe based on AIE and TICT effects for the detection of the hypochlorite anion and its bioimaging in living cells

“…In our previous work, a NIR fluorescent probe was synthesized for the detection of ClO − , but the water ratio was not so high. 12 Herein, we designed a novel AIEgen SWJT-12 to detect ClO − (Scheme 1) with a much higher water ratio. SWJT-12 also served as an excellent ratiometric fluorescent probe with low toxicity, high performance and a large Stokes shift.…”

A Rapid Near-Infrared Fluorescent Probe Based on Isophorone and its Application in B16 Cell Imaging

“…In connection with our NIR probes for biologically species and biothiols probes, [23][24][25][26][27][28] herein we report a new NIR uorescent probe (SWJT-5) with large Stokes shift (205 nm). It could be used for speci c and sensitive detection of Cys over various amino acids including Hcy and GSH in aqueous solution.…”