A new therapeutic approach for the treatment of cystic echinococcosis: percutaneous albendazole sulphoxide injection without reaspiration

In vitro effectiveness of acidic and alkline solutions on scolices of hydatid cyst

“…It is known that scolicidal solution injection in the cysts or the biliary system leads to a rise in liver enzyme level. It has also been shown that systemically administered ABZ can lead to the same changes (Deger et al 2000;Yetim et al 2005;Gil-Grande et al 1993). An ideal scolicidal agent is define as being potent in low concentrations, acting in a short period time, being stable in cyst fluid, not affected by dilution with the cyst fluid, being able to kill the scolex in the cyst, being non-toxic, having low viscosity, and being readily available and easily prepared, as well as being inexpensive (WHO 1996;Puryan et al 2005).…”

Management of hepatic hydatidosis by laparoscopic approach in rural central India: a 3 year experience

“…20 Surgery remains the mainstay of treatment for hepatic echinococcosis. 10,11 Several nonsurgical options have been explored. The first report of laparoscopic treatment of hydatid cyst of the liver was published in 1994 21 followed soon thereafter by the first report of anaphylactic shock complicating laparoscopic treatment of hydatid cysts of the liver.…”

“…8,9 Despite advances in medical treatment and in interventional radiology, the surgical approach remains the gold standard. 10,11 Only medical treatment, without surgery of liver echinococcosis with albendazole or mebendazole remains controversial. 12 Laparoscopy, as minimally invasive surgery, has well known clinical advantages over traditional surgery.…”

Hydatid cyst of liver: different modalities of management and outcome

“…However, percutaneous puncture and aspiration of the cyst, injection of scolex eliminating substance and reaspiration (PAIR) combined with chemotherapy has emerged as an alternative treatment. [5][6][7] Mebendazole and albendazole are used as medical treatment. 8,9 There are recent studies mentioning successful results with albendazole injected into the cyst.…”