1991
DOI: 10.1055/s-2007-1013921 View full text |Buy / Rent full text
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Abstract: There are some problems in surgical treatment for those patients with small branches or diffuse stenotic lesions of the coronary arteries, for whom coronary artery bypass grafting can not be carried out at all. To resolve these problems, we have planned to supply arterial blood from the left ventricle into the ischemic myocardium through holes cut into the myocardium by laser. It was clearly recognized that arterial blood could be hemodynamically supplied from the left ventricle into the ischemic myocardium. I… Show more

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“…3 During operation, which is performed on the beating heart through a left thoracotomy, a high energy laser is used to bore transmural channels into the left ventricle so that blood flows directly from the left ventricle into the channels and then into the myocardial vascular plexus. 4 Restoring perfusion should alleviate ischaemia in a potentially viable myocardium and improve ventricular function. Postoperative thallium stress tests and left ventriculography indicate that the channels remain patent and protect the ischaemic muscle.…”
Section: Discussionmentioning
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“…3 During operation, which is performed on the beating heart through a left thoracotomy, a high energy laser is used to bore transmural channels into the left ventricle so that blood flows directly from the left ventricle into the channels and then into the myocardial vascular plexus. 4 Restoring perfusion should alleviate ischaemia in a potentially viable myocardium and improve ventricular function. Postoperative thallium stress tests and left ventriculography indicate that the channels remain patent and protect the ischaemic muscle.…”
Section: Discussionmentioning
“…These findings disclosed the feasibility of the long-term patency of the newly created channels and of clinical application. [4][5] …”
Section: ) Histological Examinationmentioning
“…However, patients with refractory angina, including severe diffuse coronary artery stenosis, small caliber coronary artery, and a history of repeated surgeries, cannot undergo CABG or PTCA, and these patients account for 12% to 15% of patients requiring myocardial revascularization therapy [3] . Surgeons and scholars have devised other techniques, including transmyocardial laser revascularization (TMLR) [4] , pro-angiogenic gene therapy [5] , cardiac denervation surgery, and endarterectomy combined with CABG [6] . Specific limitations preclude wide acceptance of these methods.…”
Section: Introductionmentioning