A new isoflavanone from Uraria crinita

Abstract

A new isoflavanone, (3S)-5,7-dihydroxy-2′,3′,4′-trimethoxy-6,5′-diprenylisoflavanone (1) and eight known compounds including five flavones (2-6), two triterpenes (7-8) and a steroid (9) were isolated from the whole plant of Uraria crinita (Leguminosae). The structure of 1 was elucidated by detailed spectroscopic means including IR, HR-ESI-MS, 1D and 2D NMR, and CD data. Compounds 1-9 were evaluated for their cytotoxicity against four human cancer cell lines KB (mouth epidermal carcinoma), HepG2 (hepatocellular carcinoma), Lu (lung carcinoma) and MCF7 (breast carcinoma). Compound 1 showed cytotoxic activity against the tested cell lines with IC 50 values of 33.2, 29.4, 59.6 and 66.8 μM, respectively.

Chemical Constituents from Roots of Sophora davidii (Franch.) Skeels and Their Glucose Transporter 4 Translocation Activities

“…The known compounds Shandougenine A (5) [14], (+)-Lirioresinol-A (6) [15], Shandougenine B (7) [14], 2-(2',4'-dihydroxyphenyl)-5,6-methylenedioxybenzofuran (8) [16], isoluteolin (9) [17], and 2',4',5,7-tetrahydroxyisoflavone (10) [18] were identified by comparison of their spectroscopic data with those in the literature.…”

The complete chloroplast genome of Uraria lagopodioides (Fabaceae)

“…(Huang et al 2010). Most of the Uraria species are medicinal plants (Rahman et al 2007;Thien et al 2019). However, no chloroplast genome resource is available for this genus.…”