This paper presents a multi-input Ćuk-derived Buck-Boost voltage source inverter (CBBVSI) for Photovoltaic (PV) systems. The proposed topology consists of a single-stage DC-AC inverter that combines both DC-DC and DC-AC stages. The DC-DC stage is used for stepping-up the voltage from the PV generator. Simultaneously, the DC-AC stage is used for interfacing the PV source with the AC grid. The topology allows three sources to utilize the antiparallel diodes for each inverter leg for transferring the energy. The proposed system exhibits several features such as a reduction of the number of components compared to typical two-stage structures, and Split-Source Inverter (SSI), and Z-Source Inverter (ZSI) topologies. Moreover, the power of each PV source can be harvested either simultaneously or separately since independent Maximum Power Point Tracking (MPPT) is performed. The system was simulated using MATLAB/SIMULINK software and a 1 kW laboratory prototype was implemented to verify the operation of the proposed CBBVSI. The numerical simulations are presented together with the experimental results, showing a good agreement.