A new determination of the 68Ga half-life and evaluation of literature data

Synthesis and Preclinical Evaluation of Novel 68Ga-DOTA-RBB as Potential PET Radiotracer for Imaging CDK4/6 in Tumors

“…Therefore, the use of CDK4/6 inhibitor analogues as novel radioactive tracers holds significant potential value in the precise early diagnosis of CDK4/6-positive tumors. 68 Ga, as a widely used radioactive isotope in clinical applications, 23 possesses numerous advantages, including a suitable half-life (67.8 min), 24 straightforward labeling methods, and easy availability. All these factors suggest that 68 Ga is a promising isotope for the labeling of novel drugs.…”

“…68 Ga, as a widely used radioactive isotope in clinical applications, possesses numerous advantages, including a suitable half-life (67.8 min), straightforward labeling methods, and easy availability. All these factors suggest that 68 Ga is a promising isotope for the labeling of novel drugs.…”