A New Concept of the Development of theAnterior Chamber Angle

Anterior segment development relevant to glaucoma

“…Cyp1b1 -/-mice (Allen et al, 1955, Maumenee 1958, Libby et al, 2003. CYP1B1 belongs to a family of monomeric, mixed function monooxygenases (Sutter et al, 1994).…”

Anterior segment development relevant to glaucoma

“…Cyp1b1 -/-mice (Allen et al, 1955, Maumenee 1958, Libby et al, 2003. CYP1B1 belongs to a family of monomeric, mixed function monooxygenases (Sutter et al, 1994).…”

Ectopic intraocular lacrimal gland tissue.

“…This is because the ciliary body grows unequally (Allen, Burian, and Braley, 1955), the greater degree of growth taking place forwards and outwards. The aberrant tissue could then grow on to the posterior surface of the cornea and the anterior surface of the iris.…”

Closed-Angle Glaucoma Significance of Sectoral Variations in Angle Depth

“…It seems unlikely that Wan abnormality in differentiation of the angle during development may account for the variations in its depth, because no evidence for an unusual amount of residual tissue supero-temporally (or a proliferation- Allen, Burian, and Braley, 1955) can be seen gonioscopically when the angle is open. It is interesting to note in this context that the usual eccentricity of the pupil in cases of congenital corectopia is above and lateral to its normal site (Duke-Elder, 1938d).…”

Anterior segment development relevant to glaucoma

“…Cyp1b1 -/-mice (Allen et al, 1955, Maumenee 1958, Libby et al, 2003. CYP1B1 belongs to a family of monomeric, mixed function monooxygenases (Sutter et al, 1994).…”

Ectopic intraocular lacrimal gland tissue.

“…This is because the ciliary body grows unequally (Allen, Burian, and Braley, 1955), the greater degree of growth taking place forwards and outwards. The aberrant tissue could then grow on to the posterior surface of the cornea and the anterior surface of the iris.…”

Closed-Angle Glaucoma Significance of Sectoral Variations in Angle Depth

“…It seems unlikely that Wan abnormality in differentiation of the angle during development may account for the variations in its depth, because no evidence for an unusual amount of residual tissue supero-temporally (or a proliferation- Allen, Burian, and Braley, 1955) can be seen gonioscopically when the angle is open. It is interesting to note in this context that the usual eccentricity of the pupil in cases of congenital corectopia is above and lateral to its normal site (Duke-Elder, 1938d).…”

Anterior segment development relevant to glaucoma

“…Cyp1b1 -/-mice (Allen et al, 1955, Maumenee 1958, Libby et al, 2003. CYP1B1 belongs to a family of monomeric, mixed function monooxygenases (Sutter et al, 1994).…”

Ectopic intraocular lacrimal gland tissue.

“…This is because the ciliary body grows unequally (Allen, Burian, and Braley, 1955), the greater degree of growth taking place forwards and outwards. The aberrant tissue could then grow on to the posterior surface of the cornea and the anterior surface of the iris.…”

Closed-Angle Glaucoma Significance of Sectoral Variations in Angle Depth

“…It seems unlikely that Wan abnormality in differentiation of the angle during development may account for the variations in its depth, because no evidence for an unusual amount of residual tissue supero-temporally (or a proliferation- Allen, Burian, and Braley, 1955) can be seen gonioscopically when the angle is open. It is interesting to note in this context that the usual eccentricity of the pupil in cases of congenital corectopia is above and lateral to its normal site (Duke-Elder, 1938d).…”