A multivariate analysis of prognostic factors in early stage hodgkin's disease

Tumour burden in early stage Hodgkin's disease: the single most important prognostic factor for outcome after radiotherapy

“…Sex has a small but significant impact on disease free survival, which is in accordance with many earlier studies (Tubiana et al, 1985;Kaplan, 1980b).…”

“…The concept of tumour burden combines the tumour size of each involved region with the number of involved regions. The number of involved regions has been shown by other studies to be of major prognostic significance (Tubiana et al, 1985;Liew et al, 1984;Thar et al, 1979;Leslie et al, 1985). As demonstrated above, however, tumour burden offers some extra prognostic information.…”

“…In the present study ESR is clearly related to tumour burden and does not give significant independent prognostic information. Combining ESR with systemic symptoms as proposed by Tubiana et al (1985) does not alter this.…”

“…ESR has also been shown to be of major prognostic significance with regard to disease free survival (Tubiana et al, 1985;Haybittle et al, 1985). Both of these studies, however, comprised both clinically and pathologically staged patients.…”

Radiotherapy for stage I Hodgkin's disease: 20 years experience at St Bartholomew's Hospital

“…The results are comparable with the published literature, if it is assumed that this patient population corresponds with that of the most favourable localised Hodgkin's disease reported by others (Hoppe et al, 1982;Cornbleet et al, 1985;Fuller et al, 1980;Tubiana et al, 1985;Mauch et al, 1988;Hagemeister et al, 1982 (Carde et al, 1988). It is further corroborated by the results reported from Boston wherein staging laparotomy was consistently performed with mantle, paraortic and splenic irradiation in stage I HD (Mauch et al, 1988).…”