volume 29, issue 1, P11-17 2014
DOI: 10.3109/02688697.2014.948808
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Abstract: Background. Obtaining intra-operative watertight closure of the dura is considered important in reducing post-operative cerebrospinal fluid (CSF) leak. The purpose of this study was to evaluate a fibrin sealant as an adjunct to sutured dural repair to obtain intra-operative watertight closure in cranial neurosurgery. Methods. This randomized, controlled multicenter study compared a fibrin sealant (EVICEL Fibrin Sealant [Human]) to sutured dural closure (Control). Subjects underwent supratentorial or posterior …

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