A modular 3D printed isothermal heat flow calorimeter for reaction calorimetry in continuous flow

Abstract

The presented continuous flow calorimeter enables process understanding of novel flow syntheses and the use of highly reactive compounds. Adaptation of the calorimeter is possible via 3D printing and due to its modular and expandable design.

Characterization of reaction enthalpy and kinetics in a microscale flow platform

“…In calorimetry, early implementations include channels with integrated thin film thermopiles [10][11][12] and microstructured devices coupled with commercially available calorimeters. 13,14 Since then various techniques have been utilized to measure heat released in microchannels: heat flux measurement utilizing thermoelectric effect, [10][11][12][15][16][17][18][19][20][21][22] energy balance based on temperature measurements with thermocouples 23 or infrared cameras, [24][25][26] or a combination of several techniques. 27 Depending on the applied method, reaction conversion is measured either directly in the microreactor by colorimetry, 20,21,24 estimated from the heat released at varied flow rates, 15,[17][18][19][20]26 or by analysing samples off-line.…”

Electrochemical oscillatory baffled reactors fabricated with additive manufacturing for efficient continuous-flow oxidations

“…The higher reactor volume would in turn enable the integration of other enabling technologies for novel applications. 8 In this regard, additive manufacturing (AM), commonly known as 3D printing, can offer new opportunities for the development of continuous-flow reactors, [9][10][11][12] advanced reactor architectures 13 and other continuous-flow applications like crystallizers, 14,15 calorimeters 16 or magnetic resonance probes. 17 The digitalisation of the fabrication process enables the coupling of advanced and lean design techniques, like computational fluid dynamics (CFD), to allow the generation of optimised reactor structures 18 and the production of reactor geometries which are easily adaptable to commercial set-ups.…”

Software-guided microscale flow calorimeter for efficient acquisition of thermokinetic data

“…For the development of accurate kinetic models that assist chemical reactor development, design and optimization, extensive knowledge of interaction between reaction kinetics and hydrodynamics is essential [4]. Thus, the interest in the development of continuous flow calorimeter increases constantly [5][6][7][8]. Moreover, the miniaturization of calorimetry enables the investigation of fast and highly exothermic reactions under safe conditions due to the superior temperature control when compared to standard batch equipment [9].…”