A Microfluidic Paper-Based Analytical Device for Type-II Pyrethroid Targets in an Environmental Water Sample

Pengpumkiat, Sumate; Nammoonnoy, Jintana; Wongsakoonkan, Watcharaporn; Konthonbut, Pajaree; Kongtip, Pornpimol

doi:10.3390/s20154107

Cited by 14 publications

(14 citation statements)

References 60 publications

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“…The conventional chromatography based methods for pyrethroid analysis [165] offer high accuracy and precision, good sensitivity, and a very low detection limit, but they are expensive, complicated, and laborious. Thus, these methods may not be suitable for rapid screening and the detection of pyrethroids in developing countries which have a low-resource setting but high risk of pesticide exposure [166]. Type II pyrethroids are a class of pyrethroids which contain an alpha cyano ester group, obtained by esterification of a cyanohydrine, often m-phenoxy benzaldehyde cyanohydrine, with a modified pyrethroic acid derivative.…”

Section: Colorimetric Assay Test For Type-ii Pyrethroidmentioning

confidence: 99%

“…Type II pyrethroids are a class of pyrethroids which contain an alpha cyano ester group, obtained by esterification of a cyanohydrine, often m-phenoxy benzaldehyde cyanohydrine, with a modified pyrethroic acid derivative. The most commonly used type-II pyrethroids are deltamethrin, cypermethrin, cyhalothrin, acrinathrin, fenpropathrin, βcyfluthrin, fenvalerate, esfenvalerate, and fluvalinate [166]. Under basic conditions these type II pyrethroids are easily hydrolyzed resulting in the formation of pyrethroic acid derivative, mphenoxybenzaldehyde and cyanide.…”

Section: Colorimetric Assay Test For Type-ii Pyrethroidmentioning

confidence: 99%

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A Review on the Colorimetric Pesticide Assay Test for Safe and Sustainable Agriculture with Special Reference to Clean Food Production

Bera¹,

Datta²,

Bose³

et al. 2022

CJAST

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Background: The World Health Organization (WHO) states that “If it is not safe, it is not food”, as it does not serve its purpose to provide proper and safe nutrition. The Food and Agriculture Organization (FAO) reiterates that Sustainable Agriculture that seeks to increase yields while limiting the need for application of pesticides or synthetic fertilizers; only can relate Food Security with Food Safety. As the second largest agrarian country of the world, India has also become one of the largest users of pesticides. Surveys have shown that Indian food is laced with one of the highest amount of toxic pesticide residues in the world. Hence, analysis of pesticide residues in food has become the governing criteria for ensuring food safety. The Food Safety and Standards Authority of India (FSSAI) have laid down science based standards towards food safety based on the Codex standards, which are the reference for the international trade in food. However, it has been found that pesticide monitoring in food is most difficult in countries where that monitoring is arguably most needed. This is because the present chromatographic techniques though can precisely determine the presence of every chemical at the minute level but the process is hugely expensive, complex, time-consuming and require specific resources and infrastructure which offer major hindrance towards regular analysis for monitoring of food safety. Especially for a country like India, with absolute dominance of marginal farmers in vegetable cultivation, lack of awareness, resource scarcity, inability to take economic risk and flaws in maintaining the standard practices w.r.t. chemical usage enhances the availability of pesticides in food product. Moreover the short time gap between the field harvest of vegetables and consumption, limits the scope for safety analysis even if the infrastructure and economics is not considered. In this background an effective, simple, and affordable method is needed to enable pesticide residue analysis in situations of limited resources more so for Safe & Sustainable Agriculture Scope & Approach: In this scenario, the Colorimetric Pesticide Assay Test can be a Real Game Changer in the Food Safety Arena and a Crucial ‘Sustainability Tool’ for Safe & Sustainable Agriculture. This test method although utilized round the globe to identify the pesticides residues both in a quantitative and qualitative manner, lack a standard protocol towards safety evaluation of vegetables in terms of detecting the presence/absence of the major pesticide groups. Another crucial point is how to measure in the most affordable and transparent manner. Then it has to be made available for small, marginal and resource poor farmers, who are more than 95% of the total farming community. Inhana Organic Research Foundation (IORF), Kolkata in collaboration with Krishi Vigyan Kendra, Nadia (ICAR) initiated a research work in June, 2020 to develop a Protocol for Colorimetric Pesticide Assay Test of vegetables with the objectives of (i) Most Authentic and Speedy Measurement of the major groups of pesticides viz. organochlorine, organophosphate, synthetic pyrethroids, carbamates and neonicotinoids, that are used during vegetable production, (ii) Identifying the collective presence/ absence of the pesticide residues up to the lowest- group specific permissible limits (same type of pesticides in terms of chemical structure) and (iii) Standardization of the Method towards its effective utilization for large scale Pesticide Residue Study in the most economical manner. The Support from IBM, India for Clean Food Production – A Safe and Sustainable Agricultural Initiative; helped in the efforts to standardize the Colorimetric Assay Test Protocol towards safety evaluation of the vegetables. The standardization process involved the analysis of more than 1200 samples of 30 major vegetables produced in India. Vegetable samples were sourced from open markets, certified organic counters and from the farmers’ field where the concept of Clean Food Program was 1st initiated by IORF in collaboration with KVK, Nadia (ICAR). Also the vegetable samples were sourced during different seasons i.e., winter (Period : November – February), monsoon (Period : July – October) and summer (Period : March – June). Key Findings & Conclusion: The newly standardized Colorimetric Pesticide Assay Test Protocol can enable detection of the collective presence/ absence of pesticides up to group specific- lowest permissible limit; for more than 90 percent of the pesticides- permitted for use in India, for most of the banned chemicals, as well as chances of residual presence in case of chemicals like DDT and its isomer. In addition; this Assay Test protocol can also be utilized for detecting the presence/ absence of toxic heavy metals such as Hg2+, Cd2+, Cu2+, Pb2+ and a wide range of other toxic substance of known/unknown origin related to human health and safety. Moreover the Colorimetric Pesticide Assay Test Protocol opens up the scope for large scale and frequent food safety analysis due to the affordable cost (1/10th to 1/15th of the Conventional Cost of Residue Analysis) and significant reduction in the analysis time (1/10th of the time required for Residue Analysis using High Performance Liquid Chromatography, HPLC).

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Section: Colorimetric Assay Test For Type-ii Pyrethroidmentioning

confidence: 99%

Section: Colorimetric Assay Test For Type-ii Pyrethroidmentioning

confidence: 99%

A Review on the Colorimetric Pesticide Assay Test for Safe and Sustainable Agriculture with Special Reference to Clean Food Production

Bera¹,

Datta²,

Bose³

et al. 2022

CJAST

View full text Add to dashboard Cite

show abstract

“…Figure shows an underlying paper micro‐PAD technology. [ 135 ] Most of these manufactured devices are presently based on inkjet printing. The method involves printing hydrophobic wax onto a filter paper to create easily programmable channels for fluid flow.…”

Section: Next‐generation Microfluidicsmentioning

confidence: 99%

Microfluidics: Recent Advances Toward Lab‐on‐Chip Applications in Bioanalysis

Sharma

2021

Adv Eng Mater

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Microfluidics is an emerging technology of flow and control of fluids in microscale volume that offers highly specialized solutions to rapid, sensitive, noninvasive analysis and measurements in various engineering applications. When combined with microelectromechanical systems (MEMSs), microfluidics technology has shown remarkable developments in small‐scale devices for biosensing, chemical solutions, and precise detection of particles at a higher rate. MEMS‐inspired microfluidics technology can contribute to the highly sensitive, recyclable, and portable sensing platforms for large‐scale integration devices. In this review, the history and developmental phases occurring in MEMS are detailed. Finally, this review is concluded with future scope and guidelines for enabling the various approaches to overcome the obstacles and the mass commercialization of microfluidic devices. Recent applications of microfluidics in biosensing are also highlighted where research should be focused in the future.

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“…Nowadays, due to their advantages in terms of portability and high efficiency, microfluidic devices receive increasing attention in many fields, such as biological and healthcare measurement [ 1 , 2 , 3 , 4 , 5 ], chemistry analysis [ 6 , 7 , 8 , 9 , 10 ], and pollution analysis [ 11 ]. Electrical conductivity is a basic and important property of electrolyte solution, biomaterial or fluid [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

A Low Excitation Working Frequency Capacitively Coupled Contactless Conductivity Detection (C4D) Sensor for Microfluidic Devices

Huang

et al. 2021

Sensors

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In this work, a new capacitively coupled contactless conductivity detection (C4D) sensor for microfluidic devices is developed. By introducing an LC circuit, the working frequency of the new C4D sensor can be lowered by the adjustments of the inductor and the capacitance of the LC circuit. The limits of detection (LODs) of the new C4D sensor for conductivity/ion concentration measurement can be improved. Conductivity measurement experiments with KCl solutions were carried out in microfluidic devices (500 µm × 50 µm). The experimental results indicate that the developed C4D sensor can realize the conductivity measurement with low working frequency (less than 50 kHz). The LOD of the C4D sensor for conductivity measurement is estimated to be 2.2 µS/cm. Furthermore, to show the effectiveness of the new C4D sensor for the concentration measurement of other ions (solutions), SO42− and Li+ ion concentration measurement experiments were also carried out at a working frequency of 29.70 kHz. The experimental results show that at low concentrations, the input-output characteristics of the C4D sensor for SO42− and Li+ ion concentration measurement show good linearity with the LODs estimated to be 8.2 µM and 19.0 µM, respectively.

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A Microfluidic Paper-Based Analytical Device for Type-II Pyrethroid Targets in an Environmental Water Sample

Cited by 14 publications

References 60 publications

A Review on the Colorimetric Pesticide Assay Test for Safe and Sustainable Agriculture with Special Reference to Clean Food Production

A Review on the Colorimetric Pesticide Assay Test for Safe and Sustainable Agriculture with Special Reference to Clean Food Production

Microfluidics: Recent Advances Toward Lab‐on‐Chip Applications in Bioanalysis

A Low Excitation Working Frequency Capacitively Coupled Contactless Conductivity Detection (C4D) Sensor for Microfluidic Devices

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