A meta-analytic review of cognitive processing therapy for adults with posttraumatic stress disorder

Asmundson, Gordon J.G.; Thorisdottir, Audur S.; Roden-Foreman, Jacob W.; Baird, Scarlett O.; Witcraft, Sara M.; Stein, Aliza T.; Smits, Jasper A.J.; Powers, Mark B.

doi:10.1080/16506073.2018.1522371

Cited by 127 publications

(72 citation statements)

References 41 publications

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“…Then, we conducted a systematic search in the databases PsycINFO and Medline for the period between 1 January 2013 and 22 September 2020. Finally, we reviewed the relevant meta-analyses on the efficacy of psychological interventions for adult PTSD published since 2013 (Asmundson et al, 2019 ; Barawi, Lewis, Simon, & Bisson, 2020 ; Bisson, van Gelderen, Roberts, & Lewis, 2020 ; Carpenter et al, 2018 ; Cipriani et al, 2018 ; Coventry et al, 2020 ; Cusack et al, 2016 ; Gallegos, Crean, Pigeon, & Heffner, 2017 ; Gerger et al, 2014 ; Grasser & Javanbakht, 2019 ; Hegberg, Hayes, & Hayes, 2019 ; Hopwood & Schutte, 2017 ; Karatzias et al, 2019 ; Khan et al, 2018 ; Kline, Cooper, Rytwinksi, & Feeny, 2018 ; Kuester, Niemeyer, & Knaevelsrud, 2016 ; Lenz, Haktanir, & Callender, 2017 ; Lewis, Roberts, Andrew, Starling, & Bisson, 2020a ; Lewis, Roberts, Bethell, Robertson, & Bisson, 2018 ; Lewis, Roberts, Gibson, & Bisson, 2020b ; Mahoney, Karatzias, & Hutton, 2019 ; Mavranezouli et al, 2020 ; Montero-Marin, Garcia-Campayo, López-Montoyo, Zabaleta-Del-Olmo, & Cuijpers, 2018 ; Morina, Malek, Nickerson, & Bryant, 2017a ; Niles et al, 2018 ; Schwartze, Barkowski, Strauss, Knaevelsrud, & Rosendahl, 2019 ; Springer, Levy, & Tolin, 2018 ; Tran & Gregor, 2016 ; Van Dis et al, 2020 ; Wilson et al, 2018 ). Inclusion criteria for the meta-analysis were: (1) RCT, (2) treatment targets primarily chronic PTSD, (3) participants older than 17 years, (4) at least ten participants per condition at post-assessment, and (5) at least 70% of the sample was diagnosed with PTSD by means of a structured interview (Bisson et al, 2013 ).…”

Section: Methodsmentioning

confidence: 99%

Study quality and efficacy of psychological interventions for posttraumatic stress disorder: a meta-analysis of randomized controlled trials

2021

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Background Research indicates that higher study quality may be associated with smaller treatment effects. Yet, knowledge about the association between study quality and treatment efficacy for posttraumatic stress disorder (PTSD) is limited. We aimed at evaluating the efficacy of psychological interventions for adult PTSD and the association between study quality and treatment effects. Methods We conducted a systematic search to identify randomized controlled trials (RCTs) that examined the efficacy of psychological interventions for chronic PTSD symptoms in adult samples with at least 70% of patients being diagnosed with PTSD by means of a structured interview. We assessed study quality using the following eight criteria from prior research: N ⩾ 50, all patients met criteria for PTSD, a treatment manual was used, therapists were trained, treatment integrity was checked, intent-to-treat analyses were applied, randomization was conducted by an independent party, and treatment outcome was conducted by blind assessors. Results The search resulted in 136 RCTs with 8978 patients. Active treatment conditions were largely effective in reducing PTSD symptoms at posttreatment and follow-up (Hedges' g = 1.09 and 0.81, respectively) when compared to passive control conditions. The comparison to active control conditions at posttreatment and follow-up resulted in medium effect sizes. A total of 14 trials met all study quality criteria and these trials produced large effect sizes when compared to passive control conditions at posttreatment and follow-up. Conclusions Overall, study quality was not significantly associated with effect size. The findings indicate that psychological interventions can effectively reduce PTSD symptoms irrespective of study quality.

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Section: Methodsmentioning

confidence: 99%

Study quality and efficacy of psychological interventions for posttraumatic stress disorder: a meta-analysis of randomized controlled trials

2021

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“…Other drugs used to treat and resolve ancillary symptoms such as intrusion and hyperarousal include aand b-blockers (38) and, more recently, novel treatments such as ketamine (39). Considered to have strong research support by the American Psychological Association and the U.S. Department of Defense and Department of Veterans Affairs, cognitive processing therapy has been successful in reducing feelings of fear and culpability in PTSD (40). Cognitive processing therapy typically consists of twelve 60-to 90-min sessions that focus on changing the patients' understanding and conceptualization of their trauma, and recently, intense versions of cognitive processing therapy have demonstrated heightened success and faster recovery (41).…”

Section: Ptsd: Diagnosis and Therapymentioning

confidence: 99%

Long-Term Clinical and Neuronuclear Imaging Sequelae of Cancer Therapy, Trauma, and Brain Injury

et al. 2019

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Learning Objectives: On successful completion of this activity, participants should be able to (1) describe clinical features and therapeutic approaches in the evaluation and management of cancer-and chemotherapy-related cognitive impairment (CRCI), posttraumatic stress disorder (PTSD), and traumatic brain injury (TBI); (2) discuss the role of neuroimaging in contributing to understanding of relationships between clinical features of CRCI, PTSD, and TBI, with aspects of underlying regional cerebral function; and (3) identify which brain processes are most consistently shown to be affected in CRCI, PTSD, and TBI.

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“…Currently, the American Psychological Association [24] and the US Department of Veterans Affairs and Department of Defense [40] considers four psychological treatments for PTSD to have strong research support. Among these empirically evaluated treatments, one of the currently most promising approaches is CPT [41, 42]. CPT was originally developed as a group treatment for rape victims.…”

Section: Introductionmentioning

confidence: 99%

A research programme to evaluate DBT-PTSD, a modular treatment approach for Complex PTSD after childhood abuse

Bohus

Schmahl

Fydrich

et al. 2019

bord personal disord emot dysregul

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Background: Posttraumatic stress disorder (PTSD) after childhood abuse (CA) is often related to severe co-occurring psychopathology, such as symptoms of borderline personality disorder (BPD). The ICD-11 has included Complex PTSD as a new diagnosis, which is defined by PTSD symptoms plus disturbances in emotion regulation, self-concept, and interpersonal relationships. Unfortunately, the empirical database on psychosocial treatments for survivors of CA is quite limited. Furthermore, the few existing studies often have either excluded subjects with self-harm behaviour and suicidal ideationwhich is common behaviour in subjects suffering from Complex PTSD. Thus, researchers are still trying to identify efficacious treatment programmes for this group of patients. We have designed DBT-PTSD to meet the specific needs of patients with Complex PTSD. The treatment programme is based on the rules and principles of dialectical behavioural therapy (DBT), and adds interventions derived from cognitive behavioural therapy, acceptance and commitment therapy and compassion-focused therapy. DBT-PTSD can be provided as a comprehensive residential programme or as an outpatient programme. The effects of the residential programme were evaluated in a randomised controlled trial. Data revealed significant reduction of posttraumatic symptoms, with large between-group effect sizes when compared to a treatment-as-usual wait list condition (Cohen's d = 1.5). The first aim of this project on hand is to evaluate the efficacy of the outpatient DBT-PTSD programme. The second aim is to identify the major therapeutic variables mediating treatment efficacy. The third aim is to study neural mechanisms and treatment sensitivity of two frequent sequelae of PTSD after CA: intrusions and dissociation. Methods: To address these questions, we include female patients who experienced CA and who fulfil DSM-5 criteria for PTSD plus borderline features, including criteria for severe emotion dysregulation. The study is funded by the German Federal Ministry of Education and Research, and started in 2014. Participants are randomised to outpatient psychotherapy with either DBT-PTSD or Cognitive Processing Therapy. Formal power analysis revealed a minimum of 180 patients to be recruited. The primary outcome is the change on the Clinician-Administered PTSD Scale for DSM-5. Discussion: The expected results will be a major step forward in establishing empirically supported psychological treatments for survivors of CA suffering from Complex PTSD. Trial registration: German Clinical Trials Register: registration number DRKS00005578, date of registration 19 December 2013.

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A meta-analytic review of cognitive processing therapy for adults with posttraumatic stress disorder

Abstract: This is a temporary placeholder file. An open access version will be added if it becomes available. Pease click on the DOI link to access the publisher version of record.

Cited by 127 publications

References 41 publications

Study quality and efficacy of psychological interventions for posttraumatic stress disorder: a meta-analysis of randomized controlled trials

Study quality and efficacy of psychological interventions for posttraumatic stress disorder: a meta-analysis of randomized controlled trials

Long-Term Clinical and Neuronuclear Imaging Sequelae of Cancer Therapy, Trauma, and Brain Injury

A research programme to evaluate DBT-PTSD, a modular treatment approach for Complex PTSD after childhood abuse

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