A Meta-Analysis of the Yield of Capsule Endoscopy Compared to Other Diagnostic Modalities in Patients with Obscure Gastrointestinal Bleeding

Triester, Stuart L.; Leighton, Jonathan A.; Leontiadis, Grigoris I; Fleischer, David E.; Hara, Amy K.; Heigh, Russell I.; Shiff, Arthur D.; Sharma, Virender K.

doi:10.1111/j.1572-0241.2005.00274.x

Cited by 581 publications

(382 citation statements)

References 22 publications

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“…It is reported SBCE was superior when compared with push enteroscopy and small bowel barium radiography for OGIB (P < 0.00001) [20] . In detecting Crohn's disease, SBCE was also superior to small bowel barium radiography (P < 0.001), colonoscopy with ileoscopy (P = 0.02) and CT (P = 0.001) [21] .…”

Section: Discussionmentioning

confidence: 99%

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

Gao²,

Liao³

et al. 2009

WJG

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AIM:To review the literature on capsule endoscopy (CE) for detecting esophageal varices using conventional esophagogastroduodenoscopy (EGD) as the standard. METHODS:A strict literature search of studies comparing the yield of CE and EGD in patients diagnosed or suspected as having esophageal varices was conducted by both computer search and manual search. Data were extracted to estimate the pooled diagnostic sensitivity and specificity. RESULTS:There were seven studies appropriate for meta-analysis in our study, involving 446 patients. The pooled sensitivity and specificity of CE for detecting esophageal varices were 85.8% and 80.5%, respectively. In subgroup analysis, the pooled sensitivity and specificity were 82.7% and 54.8% in screened patients, and 87.3% and 84.7% in the screened/ patients under surveillance, respectively.CONCLUSION: CE appears to have acceptable sensitivity and specificity in detecting esophageal varices. However, data are insufficient to determine the accurate diagnostic value of CE in the screen/ surveillance of patients alone.

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Section: Discussionmentioning

confidence: 99%

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

Gao²,

Liao³

et al. 2009

WJG

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“…CE has established indications in obscure gastrointestinal bleeding (OGIB), suspected Crohn's disease and small bowel tumors, surveillance in patients with polyposis syndromes, and suspected or refractory malabsorptive syndromes such as celiac disease [3,4]. Its diagnostic yield is very good when compared with other diagnostic methods, and has a positive impact on clinical management [5][6][7][8][9][10][11][12][13]. However, the diagnostic yield depends on the enteroscopy completion rates to the cecum.…”

Section: Background and Aimsmentioning

confidence: 99%

The Effect of Metoclopramide in Capsule Enteroscopy

et al. 2009

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Clinical utility of prokinetics in capsule endoscopy (CE) is not clearly established. The objective of this prospective, randomized, single-blind, controlled trial was to determine if metoclopramide is useful in CE by increasing the rate of complete enteroscopy. Ninety-five patients referred for CE were randomized to no metoclopramide (group B, n = 48) or 10 mg metoclopramide (group A, n = 47). Complete enteroscopy was possible in 38 patients of group A (80.9%) and 37 of group B (77.1%) (P = 0.422) with two cases of gastric retention in group B (4.2%; P = 0.253). Median gastric transit time was 26 min (1-211) in group A and 28 min (4-200) in group B (P = 0.511). Mean small bowel transit time, calculated after excluding 20 patients with incomplete enteroscopy, was similar in both groups (221.2 ± 89 min vs. 256 ± 82.2 min; P = 0.083). There were also no differences in the total number of findings (group A 4.5 ± 4.7; group B 4.7 ± 3.7, P = 0,815). Administration of 10 mg metoclopramide orally 15 min before capsule ingestion did not significantly increase the rate of total enteroscopies and had no effect on transit times. It also did not modify CE diagnostic yield.

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“…Según datos aportados por la literatura, la capacidad que tiene este examen de encontrar lesiones en intestino delgado que expliquen con claridad la pérdida de sangre es de aproximadamente 60% [16][17][18] . Entre las lesiones más frecuentes que se pueden visualizar, se encuentran lesiones vasculares, erosiones y úlceras.…”

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Utilidad de la cápsula endoscópica como método diagnóstico en el estudio de patología de intestino delgado

Ibáñez

Araya

et al. 2010

Rev. méd. Chile

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A Meta-Analysis of the Yield of Capsule Endoscopy Compared to Other Diagnostic Modalities in Patients with Obscure Gastrointestinal Bleeding

Cited by 581 publications

References 22 publications

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

Meta-analysis of capsule endoscopy in patients diagnosed or suspected with esophageal varices

The Effect of Metoclopramide in Capsule Enteroscopy

Utilidad de la cápsula endoscópica como método diagnóstico en el estudio de patología de intestino delgado

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