A Histopathological Comparison of “Char-free” Carbon Dioxide Lasers

Kauvar, Arielle N. B.; Waldorf, Heidi A.; Geronemus, Roy G.

doi:10.1111/j.1524-4725.1996.tb00328.x

Cited by 73 publications

(69 citation statements)

References 34 publications

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“…At commonly utilized parameters, the zone of residual thermal damage (RTD) is typically 20±50 mm deep. This results in faster skin re-epithelialization as compared to deeper penetrating lasers, such as the CO 2 , [3±6], which induce a 60±150 mm thick zone of RTD [7,8].…”

Section: Introductionmentioning

confidence: 99%

Er:YAG laser skin resurfacing using repetitive long‐pulse exposure and cryogen spray cooling: I. Histological study*

et al. 2001

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Background and Objective: To evaluate histologically the characteristics of repetitive Er:YAG laser exposure of skin in combination with cryogen spray cooling (CSC), and its potential as a method of laser skin resurfacing. Study Design/Materials and Methods: Rat skin was irradiated in vivo with sequences of 10 Er:YAG laser pulses (repetition rate 20 Hz, pulse duration 150 or 550 ms, single-pulse¯uence 1.3±5.2 J/cm 2 ). In some examples, CSC was applied to reduce epidermal injury. Histologic evaluation was performed 1 hour, 1 day, 5 days, and 4 weeks post-irradiation. Results: A sequence of ten 550-ms pulses with¯uences around 2 J/cm 2 resulted in acute dermal collagen coagulation to a depth of approximately 250 mm, without complete epidermal ablation. CSC improved epidermal preservation, but also diminished the coagulation depth. Four weeks after irradiation, neo-collagen formation was observed to depths in excess of 100 mm. Conclusion: Dermal collagen coagulation and neo-collagen formation to depths similar to those observed after CO 2 laser resurfacing can be achieved without complete ablation of the epidermis by rapidly stacking long Er:YAG laser pulses. Application of CSC does not offer signi®cant epidermal protection for a given dermal coagulation depth.

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Section: Introductionmentioning

confidence: 99%

Er:YAG laser skin resurfacing using repetitive long‐pulse exposure and cryogen spray cooling: I. Histological study*

et al. 2001

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“…Kauvar et al histologically demonstrated that the CO 2 laser, in both the pulse and continuous modes allowed superficial ablation with minimal thermal damage. 13 Some studies like Dobry et al study also affirmed that the pulse mode caused less thermal damage,but that a longer actuation time was needed with the tissue.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Carbon Dioxide Laser With Surgical Blade for Removal of Epulis Fissuratum. A Randomized Clinical Trial

et al. 2016

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“…Improvements in laser technology by use of the theory of selective photothermolysis have enabled the use of pulsed laser systems which minimize thermal damage to noninvolved tissue. 28 ,29…”

Section: Discussionmentioning

confidence: 99%

Aesthetic CO2 laser surgery: Evaluation of 907 patients1

Roberts

Weinstein

Alexandrides

et al. 1997

Aesthetic Surgery Journal

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A Histopathological Comparison of “Char-free” Carbon Dioxide Lasers

Abstract: The pulsed and scanned technologies are capable of producing "char-free" tissue ablation with minimal residual thermal damage.

Cited by 73 publications

References 34 publications

Er:YAG laser skin resurfacing using repetitive long‐pulse exposure and cryogen spray cooling: I. Histological study*

Er:YAG laser skin resurfacing using repetitive long‐pulse exposure and cryogen spray cooling: I. Histological study*

Comparison of Carbon Dioxide Laser With Surgical Blade for Removal of Epulis Fissuratum. A Randomized Clinical Trial

Aesthetic CO2 laser surgery: Evaluation of 907 patients1

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