A highly sensitive and stable electrochemical sensor for simultaneous detection towards ascorbic acid, dopamine, and uric acid based on the hierarchical nanoporous PtTi alloy

Zhao, Dan; Guo, Yu; Tian, Kunlong; Xu, Caixia

doi:10.1016/j.bios.2016.03.074

Cited by 256 publications

(43 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The detection limit of the UA biosensor was estimated to be about 0.01 μM (S/N = 3). It was obvious that MIT/TiO 2 nanoparticle/QCM electrode exhibited superior linear range and lower detection limit to UA molecules while comparing with the previously reported UA sensors (Table ), which guaranteed its possible applications.…”

Section: Resultsmentioning

confidence: 57%

“…Over the low concentration range (0.04-45 μM), good linearity was obtained, as illustrated in Figure 6B. (Table 1), [7][8][9]11,12,34,35 which guaranteed its possible applications.…”

Section: Biosensing Performancementioning

confidence: 72%

“…1,2 Recently, the low UA level in the serum and/or cerebrospinal fluid has been proved to be a key biomarker of Parkinson disease. 3 In the past years, some analytical methods have been developed for UA detection, including highperformance liquid chromatography (HPLC), 4 chemiluminescence, 5 electrochemistry, [6][7][8] enzymatic assay, 9,10 fluorescence, 11,12 surface plasmon resonance, 3 and photoelectrochemistry. 11,12 Despite many advances in UA detection, many of these methods still do not meet the growing demand for more sensitive and selective detection of UA.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition

Zhang¹,

Xiao

Qin

et al. 2018

J of Molecular Recognition

View full text Add to dashboard Cite

Combining the surface modification and molecular imprinting technique, a novel piezoelectric sensing platform with excellent molecular recognition capability was established for the detection of uric acid (UA) based on the immobilization of TiO2 nanoparticles onto quartz crystal microbalance (QCM) electrode and modification of molecularly imprinted TiO2 (MIT) layer on TiO2 nanoparticles. The performance of the fabricated biosensor was evaluated, and the results indicated that the biosensor exhibited high sensitivity in UA detection, with a linear range from 0.04 to 45 μM and a limit of detection of 0.01 μM. Moreover, the biosensor presented high selectivity towards UA in comparison with other interferents. The analytical application of the UA biosensor confirmed the feasibility of UA detection in urine sample.

show abstract

Section: Resultsmentioning

confidence: 57%

“…Over the low concentration range (0.04-45 μM), good linearity was obtained, as illustrated in Figure 6B. (Table 1), [7][8][9]11,12,34,35 which guaranteed its possible applications.…”

Section: Biosensing Performancementioning

confidence: 72%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition

Zhang¹,

Xiao

Qin

et al. 2018

J of Molecular Recognition

View full text Add to dashboard Cite

show abstract

“…Some shortcomings of these methods, such as expensive, complex, and unbefitting for real clinical analysis (Da Costa et al, ), are undeniable. By contrast, electrochemical biosensor is an attractive alternative due to its simplicity, low cost, excellent selectivity, and high sensitivity (Wang, Gao, Sun, & Xu, ; Xu, Liu, Su, Liu, & Qiu, ; Zhao, Yu, Tian, & Xu, ). Electrochemical applications of biosensors such as uric acid biosensors based on enzyme catalytic reactions are reported in the documents (Brusova, Ferapontova, Sakharov, Magner, & Gorton, ; Dai, Bao, & Yang, ; Dung, Patil, & Duong, ; Shimomura, Itoh, & Sumiya, ).…”

Section: Introductionmentioning

confidence: 99%

Potential of a sensitive uric acid biosensor fabricated using hydroxyapatite nanowire/reduced graphene oxide/gold nanoparticle

Chen

Zhou

et al. 2019

Microscopy Res & Technique

View full text Add to dashboard Cite

In this study, a ternary nanocomposite consisting of gold nanoparticles (AuNPs), hydroxyapatite (HAP) nanowires, and reduced graphene oxide (rGO) is synthesized by a simple one‐step hydrothermal method, which is used to modify glassy carbon electrode (GCE) for detecting uric acid. The nanocomposite is characterized through various methods such as scanning electron microscopy, transmission electron microscopy, and X‐ray diffraction. Electrochemical measurements of the modified GCE are performed in a conventional three‐electrode system. Experimental results show that the obtained HAP nanowire and rGO are mixed homogeneously, and the AuNPs are deposited into this matrix. The GCE modified by the nanocomposites have superior electrocatalytic activities for uric acid. The peak current intensities of UAO (uricase)/HAP‐rGO/AuNPs sensing system linearly increase as the uric acid concentration increases substantially in a range of 1.95 × 10−5 to 6.0 × 10−3 M (R2 = .9943), with a detection limit of 3.9 × 10−6 M (S/N = 3) and analytical sensitivity of 13.86 mA/M. The biosensor performs well in determining uric acid concentration in human urine samples.

show abstract

“…Nanostructured Pt-based materials have garnered increasing attention over the last decade, in the areas of electrocatalysis and sensors, through the provision of high surface area to volume ratios, as well as the capacity to be tailored to encourage particular reaction pathways [27,28,29,30,31,32,33]. Morphologically dependent interatomic bond distances, melting points, chemical reactivity, as well as optical and electronic properties can have profound influences on the functionality of Pt nanomaterials.…”

Section: Introductionmentioning

confidence: 99%

Design and Electrochemical Study of Platinum-Based Nanomaterials for Sensitive Detection of Nitric Oxide in Biomedical Applications

2016

View full text Add to dashboard Cite

The extensive physiological and regulatory roles of nitric oxide (NO) have spurred the development of NO sensors, which are of critical importance in neuroscience and various medical applications. The development of electrochemical NO sensors is of significant importance, and has garnered a tremendous amount of attention due to their high sensitivity and selectivity, rapid response, low cost, miniaturization, and the possibility of real-time monitoring. Nanostructured platinum (Pt)-based materials have attracted considerable interest regarding their use in the design of electrochemical sensors for the detection of NO, due to their unique properties and the potential for new and innovative applications. This review focuses primarily on advances and insights into the utilization of nanostructured Pt-based electrode materials, such as nanoporous Pt, Pt and PtAu nanoparticles, PtAu nanoparticle/reduced graphene oxide (rGO), and PtW nanoparticle/rGO-ionic liquid (IL) nanocomposites, for the detection of NO. The design, fabrication, characterization, and integration of electrochemical NO sensing performance, selectivity, and durability are addressed. The attractive electrochemical properties of Pt-based nanomaterials have great potential for increasing the competitiveness of these new sensors and open up new opportunities in the creation of novel NO-sensing technologies for biological and medical applications.

show abstract

A highly sensitive and stable electrochemical sensor for simultaneous detection towards ascorbic acid, dopamine, and uric acid based on the hierarchical nanoporous PtTi alloy

Cited by 256 publications

References 53 publications

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition

Potential of a sensitive uric acid biosensor fabricated using hydroxyapatite nanowire/reduced graphene oxide/gold nanoparticle

Design and Electrochemical Study of Platinum-Based Nanomaterials for Sensitive Detection of Nitric Oxide in Biomedical Applications

Contact Info

Product

Resources

About

A highly sensitive and stable electrochemical sensor for simultaneous detection towards ascorbic acid, dopamine, and uric acid based on the hierarchical nanoporous PtTi alloy

Cited by 256 publications

References 53 publications

Modification of nanocrystalline TiO2 coatings with molecularly imprinted TiO2 for uric acid recognition

Modification of nanocrystalline TiO2 coatings with molecularly imprinted TiO2 for uric acid recognition

Potential of a sensitive uric acid biosensor fabricated using hydroxyapatite nanowire/reduced graphene oxide/gold nanoparticle

Design and Electrochemical Study of Platinum-Based Nanomaterials for Sensitive Detection of Nitric Oxide in Biomedical Applications

Contact Info

Product

Resources

About

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition

Modification of nanocrystalline TiO₂ coatings with molecularly imprinted TiO₂ for uric acid recognition