A Highly Selective and Sensitive Detection of Ellagic Acid by Using Ethylenediamine Ligand Based Cobalt (II) Complex Modified Glassy Carbon Electrode

Abstract

We have successfully prepared simple and sensitive ethylenediamine ligand based cobalt (II) inorganic complex ([Co(en) 3 ] 2+ ) (en = ethylenediamine) modified glassy carbon electrode (GCE) and used for the electro chemical detection of Ellagic acid (EA). The prepared inorganic complex was characterized by the suitable physical and chemical characterization technique. Moreover, the modified electrode performance was monitored by the cyclic voltammetric (CV) and amperometric technique (it). Besides, the GCE/[Co(en) 3 ] 2+ electrode has remarkably enhance the electrocatalytic activity towards the detection of EA. Using the optimized condition, the sensor exhibited the linear detection response range (0.1µM-929µM) with the limit detection (0.035 nM) and the sensitivity is (0.06709 µA µM cm -2 ). Furthermore, the fabricated electrode is an exhibited the acceptable repeatability, reproducibility and stability. On the other hand, the GCE/[Co(en) 3 ] 2+ modified electrodes have been applied for the real sample analysis, which exhibit the acceptable recovery. The practical application of the modified electrode was successfully applied for the determination of EA from the real samples with good recovery.

Potentiodynamic Poly(resorcinol)-Modified Glassy Carbon Electrode as a Voltammetric Sensor for Determining Cephalexin and Cefadroxil Simultaneously in Pharmaceutical Formulation and Biological Fluid Samples

“…In this regard, no electrochemical methods have been reported for the simultaneous determination of CLN and CFL. The electrochemical performance of a working electrode is usually improved with surface modification by enhancing its compatibility, electron conductivity, and surface area. , Conducting polymers, , metal-based nanomaterials, and transition metal complexes ,− are among the commonly reported electrode-modifying materials which are deposited on the surface of the electrode by potentiostatic electropolymerization, potentiodynamic electropolymerization, , and casting techniques . Hence, this work demonstrated the development and evaluation of an electrochemical sensor based on the poly­(reso)/GCE for the simultaneous determination of CLN and CFL in tablet formulations, human urine, and human serum samples using a square wave voltammetric method (preparation explained in the experimental section of the Supporting Information).…”

Synthesis of AgNPs/MnO2/rGO composite materials with adsorption properties and their application in analysis of anti-inflammatory and antibiotic agents

“…(7) dử dụng vật liệu AgNPs/GO để hấp phụ và loại bỏ phẩm màu xanh methylen (MB) và methyl da cam (MO). Tác giả Chen S. M. đã sử dụng MnO2/GO và Ag/GO để xác định hydrazine và Asen (8).…”

Biosensors and Sensing Systems for Rapid Analysis of Phenolic Compounds from Plants: A Comprehensive Review

“…A similar sensor was built using a cobalt (II) ethylenediamine complex to detect ellagic acid [ 111 ]. A 35 pM LOD was obtained, and the sensor resulted selective when tested toward dopamine, acetaminophen, catechol, hydroquinone, gallic acid, uric acid, ascorbic acid, and morin.…”