A Growth-Retarding Factor in Maize Bran

Borrow, A.; Fowden, L.; Stedman, M.M.; Waterlow, J. C.; Webb, Robyn

doi:10.1016/s0140-6736(48)90771-5

Cited by 12 publications

(2 citation statements)

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“…For the next three years, Leslie worked under the direction of the Unit's Deputy Director, Dr R. A. Webb, on two projects. The first related to the Unit's interests in kwashiorkor and investigated a growth-retarding factor in maize bran (1). The second project was a chromatographic study of peanut protein hydrolysates and their free amino acid content (2), which provided the stimulus for much of Leslie's subsequent research.…”

Section: Academic Career Scientific Contributions and Impact On Agricultural Researchmentioning

confidence: 99%

Sir Leslie Fowden. 13 October 1925—16 December 2008

Fowden

Anderson

Lea

2021

Biogr. Mems Fell. R. Soc.

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Professor Sir Leslie Fowden was an organic chemist and one of the most influential plant scientists of his generation. He pioneered the new field of phytochemistry and was the world authority on plant amino acids. He was distinguished for the identification, characterization and biological function of a new category of nitrogen containing molecules in plants, the non-protein amino acids. During his research career, he isolated at least 50 of these compounds from a wide range of different plant genera and established their structural diversity, metabolic and toxic functions, and their scientific significance. In achieving this, he developed novel techniques for the rapid, quantitative separation of compounds by chromatography and electrophoresis, which were widely adopted in other disciplines. As Director of Rothamsted Experimental Station, he opened up new areas of research in plant biochemistry and molecular biology, and became an effective voice for the importance of agricultural research in the UK. He provided strategic leadership in the translational application of plant biochemistry to the agrichemical industry and to global crop resistance and production. His discoveries established the complexity and central role of plant nitrogen metabolism in plant growth and laid the foundations for current research in plant sciences aimed at improving both food security and the nutritional value of plants.

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Section: Academic Career Scientific Contributions and Impact On Agricultural Researchmentioning

confidence: 99%

Sir Leslie Fowden. 13 October 1925—16 December 2008

Fowden

Anderson

Lea

2021

Biogr. Mems Fell. R. Soc.

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“…Woolley's working hypothesis is that the toxamin may be a pyridine compound possibly related to 3-acetylpyridine. Borrow, Fowden, Stedman, Waterlow & Webb (1948) found that maize bran was particularly effective in producing a nicotinic acid deficiency in rats.…”

Section: Boxyl-p-aminobenzoylglutamic Acid) Nicotinamidementioning

confidence: 99%