2003
DOI: 10.1074/jbc.m309472200
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Abstract: A fine control of the blood glucose level is essential to avoid hyper-or hypo-glycemic shocks associated with many metabolic disorders, including diabetes mellitus and type I glycogen storage disease. Between meals, the primary source of blood glucose is gluconeogenesis and glycogenolysis. In the final step of both pathways, glucose-6-phosphate (G6P) is hydrolyzed to glucose by the glucose-6-phosphatase (G6Pase) complex. Because G6Pase (renamed G6Pase-␣) is primarily expressed only in the liver, kidney, and i… Show more

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