A Fluorescent One-Dimensional Photonic Crystal for  Label-Free Biosensing Based on Bloch Surface Waves

Frascella, Francesca; Ricciardi, Serena; Rivolo, Paola; Moi, Valeria; Giorgis, Fabrizio; Descrovi, Emiliano; Michelotti, Francesco; Munzert, Peter; Danz, Norbert; Napione, Lucia; Alvaro, Maria; Bussolino, Federico

doi:10.3390/s130202011

Cited by 59 publications

(50 citation statements)

References 32 publications

(29 reference statements)

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“…Organic nonlinear optical crystals have many applications in biological labelling [8,9]. Fluorescent crystals can be used for bio sensing, optical data storage, document security, detecting forgery [10], and photo induced electron transfer property for light harvesting [11,12]. By exploiting their exceptional properties, C-dots can replace semiconductor metal quantum dots such as CdSe, CdTe, and CdS, which involve extremely harmful precursors [13,14] as well as complex procedures for their synthesis.…”

Section: Introductionmentioning

confidence: 99%

Non-blinking dendritic crystals from C-dot solution

Mewada¹,

Vishwakarma²,

Patil³

et al. 2015

Carbon letters

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Bio-imaging and drug carriers for delivery have created a huge demand for crystals. Crystals are fascinating materials that have been grown for a long time but obtaining biocompatible fluorescent crystals is a challenging task. We report on the growth of fluorescent crystals using a carbon dot (C-dot) solution by a hydrothermal process. The crystallization pattern of these C-dots exhibited a unique dendritic structure having a feather-like morphology. The growth temperature and pressure were maintained at 60°C and 200 mmHg, respectively, for crystal growth. A green fluorescence (under UV light) that was observed in the C-dot solution was retained in the crystals formed from the solution. Cytotoxicity studies on Vero cells revealed the crystals to be extremely biocompatible. These fluorescent crystals are extremely well suited for biomedical and optoelectronic applications.

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Section: Introductionmentioning

confidence: 99%

Non-blinking dendritic crystals from C-dot solution

Mewada¹,

Vishwakarma²,

Patil³

et al. 2015

Carbon letters

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show abstract

“…They have received much attention in recent years, mostly because of their potential in sensing. BSW-based gas, protein, antibody, glucose, and protease detectors as well as BSW-induced enhanced Raman scattering have been successfully demonstrated [6][7][8][9][10][11][12][13]. Different effects in the presence of BSWs have been experimentally observed including the enhancement of fluorescence [14] and magneto-optical effects [15], giant Goos-Hänchen effect [16], and BSW-induced radiation forces [17,18].…”

Section: Introductionmentioning

confidence: 99%

Bloch Surface Wave Photonic Device Fabricated by Femtosecond Laser Polymerisation Technique

et al. 2018

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Abstract:We applied femtosecond laser polymerisation technique to fabricate a novel Bloch surface wave integrated photonic device with a compact coupling scheme. The device consisted of a waveguide, coupling and decoupling gratings and focusing and defocusing triangles. We manufactured an array of devices with varying geometrical parameters of waveguide. Excitation and propagation of Bloch surface wave waveguide modes were studied by direct and back focal plane imaging. The obtained results prove that the maskless and flexible femtosecond laser polymerisation technique may be applied for fabrication of Bloch-surface-wave based integrated photonics.

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“…A refractive index sensor consisting of a 1-D photonic crystal embedded in a microfluidic channel has been investigated, yielding a sensitivity of 836 nm RIU −1 for several ethanol solutions (Nunes et al, 2010). A 1-D photonic crystal has been used as an optical transducer for biosensing upon the coupling of Bloch surface waves (Frascella et al, 2013). In this design, the photonic structure exhibits an emissive behavior and the fluorescence shift is used as a means for detecting refractive index variations occurring at the 1-D photonic crystal surface.…”

Section: Introductionmentioning

confidence: 99%

“…It is now possible to fabricate 1-D photonic crystals with layer thicknesses reaching the nanometer scale. 1-D dielectric multilayer structures, or photonic crystals, have been used in many photonic devices as filters (Vangala et al, 2014), microcavities (Chen et al, 2014b) and optical sensors (Sreekantha et al, 2013;Chen et al, 2014a;Frascella et al, 2013;Nunes et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Refractive index sensing of gases based on a one-dimensional photonic crystal nanocavity

Mohebbi

2015

J. Sens. Sens. Syst.

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Abstract. Silicon photonic crystal sensors have become very attractive for various optical sensing applications. Using silicon as a material platform provides the ability to fabricate sensors with other photonic devices on a single chip. In this paper, a new optical sensor based on optical resonance in a one-dimensional silicon photonic crystal with an air defect is theoretically studied for refractive index sensing in the infrared wavelength region. The air defect introduces a cavity into the photonic crystal, making it suitable for probing the properties of a gas found within the cavity. This photonic crystal nanocavity is designed to oscillate at a single mode with a high quality factor, allowing for refractive index sensing of gases with a high sensitivity. A method is presented to maximize the sensitivity of the sensor and to obtain a very narrow bandwidth cavity mode for good sensor resolution. We change the thickness of the air layers linearly in the photonic crystals on both sides of the nanocavity and show that a sensitivity of 1200 nm RIU −1 can be achieved. We present a detailed analysis of the sensor and variations of the layer thicknesses, the cavity length, and the number of periodic layers in the photonic crystal are investigated. This optical sensor has a much simpler design and higher sensitivity compared to other photonic crystal sensors reported previously.

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A Fluorescent One-Dimensional Photonic Crystal for Label-Free Biosensing Based on Bloch Surface Waves

Cited by 59 publications

References 32 publications

Non-blinking dendritic crystals from C-dot solution

Non-blinking dendritic crystals from C-dot solution

Bloch Surface Wave Photonic Device Fabricated by Femtosecond Laser Polymerisation Technique

Refractive index sensing of gases based on a one-dimensional photonic crystal nanocavity

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