Wright, J. T. M. (1977). Thorax, 32,[296][297][298][299][300][301][302]. An in-vitro assessment of the hydraulic characteristics of the Mark II Abrams-Lucas mitral valve prosthesis. As a result of the durability problems associated with the first Abrams-Lucas mitral valve, a redesigned model has recently been introduced into limited clinical trials. The new valve was subjected to in-vitro pulsatile flow studies, and measurements were made of mean diastolic pressure gradient and volume of reflux on closure. Similar measurements were made on other mitral valve prostheses of comparable size. High-speed cinematography was used to analyse the motion of the occluder during the simulated cardiac cycle, and the flow patterns produced by the valve in the model ventricular cavity were observed and photographed.The pressure gradient of the Abrams-Lucas valve was significantly lower than that of the 29 mm Bj6rk-Shiley valve and all other prostheses tested, but its reflux level was higher at 12 ml per stroke. The valve opened and closed smoothly and the flow visualisation study revealed that the valve produced a large vortex or swirl in the model ventricular cavity.The first Abrams-Lucas mitral valve prosthesis underwent limited clinical trials a decade ago (Abrams, 1968) and proved to be haemodynamically satisfactory as a mitral valve replacement.The limited experience gained from the 40 or so surviving patients indicated that the incidence of thromboembolic complication associated with the prosthesis was appreciably less than that associated with the Starr-Edwards model 6120 silicone .A. rubber ball valve which was inserted into a similar group of patients at the same centre (Abrams, 1976). However, the durability of the prosthesis was found to be inadequate because there was significant wear of the hooks which retained the flap to the orifice. This wear limited the useful life of the valve to five to seven years. Figure 1 shows