A Family With a Hereditary Fatal Disease

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

“…Impaired psychosocial outcomes and maladaptive coping, such as isolating oneself, denial, and avoidance, often coexist. These behaviors may moderate the relationship between disease burden and psychological outcomes [ 49,58 ]. In contrast, dispositional optimism and positive thinking have been associated with improved mental well-being and may serve as markers of resilience [ 26,35 ].…”

“…Contributing factors included sustained uncertainty about the future, fear of rejection, frustration over screening, and perceived social isolation [ 54,56 ]. A standardized personality inventory showed elevated scores across several psychological domains (e.g., anxiety, hypochondriasis, and social withdrawal), consistent with maladaptive personality traits and linked to pronounced fear of death, though findings lack replication [ 49 ]. Notably, 40% of family members experienced elevated distress, emphasizing the broader psychosocial impact [ 52 ].…”

“…Limited data are available. One study described denial and social withdrawal as coping strategies to potentially mute feelings and anxiety [ 49 ]. Two studies noted patients felt misunderstood, citing poor communication with others and inadequate social or expert support [ 53,54 ].…”

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

“…Impaired psychosocial outcomes and maladaptive coping, such as isolating oneself, denial, and avoidance, often coexist. These behaviors may moderate the relationship between disease burden and psychological outcomes [ 49,58 ]. In contrast, dispositional optimism and positive thinking have been associated with improved mental well-being and may serve as markers of resilience [ 26,35 ].…”

“…Contributing factors included sustained uncertainty about the future, fear of rejection, frustration over screening, and perceived social isolation [ 54,56 ]. A standardized personality inventory showed elevated scores across several psychological domains (e.g., anxiety, hypochondriasis, and social withdrawal), consistent with maladaptive personality traits and linked to pronounced fear of death, though findings lack replication [ 49 ]. Notably, 40% of family members experienced elevated distress, emphasizing the broader psychosocial impact [ 52 ].…”

“…Limited data are available. One study described denial and social withdrawal as coping strategies to potentially mute feelings and anxiety [ 49 ]. Two studies noted patients felt misunderstood, citing poor communication with others and inadequate social or expert support [ 53,54 ].…”

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

“…Impaired psychosocial outcomes and maladaptive coping, such as isolating oneself, denial, and avoidance, often coexist. These behaviors may moderate the relationship between disease burden and psychological outcomes [ 49,58 ]. In contrast, dispositional optimism and positive thinking have been associated with improved mental well-being and may serve as markers of resilience [ 26,35 ].…”

“…Contributing factors included sustained uncertainty about the future, fear of rejection, frustration over screening, and perceived social isolation [ 54,56 ]. A standardized personality inventory showed elevated scores across several psychological domains (e.g., anxiety, hypochondriasis, and social withdrawal), consistent with maladaptive personality traits and linked to pronounced fear of death, though findings lack replication [ 49 ]. Notably, 40% of family members experienced elevated distress, emphasizing the broader psychosocial impact [ 52 ].…”

“…Limited data are available. One study described denial and social withdrawal as coping strategies to potentially mute feelings and anxiety [ 49 ]. Two studies noted patients felt misunderstood, citing poor communication with others and inadequate social or expert support [ 53,54 ].…”

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

“…Impaired psychosocial outcomes and maladaptive coping, such as isolating oneself, denial, and avoidance, often coexist. These behaviors may moderate the relationship between disease burden and psychological outcomes [ 49,58 ]. In contrast, dispositional optimism and positive thinking have been associated with improved mental well-being and may serve as markers of resilience [ 26,35 ].…”

“…Contributing factors included sustained uncertainty about the future, fear of rejection, frustration over screening, and perceived social isolation [ 54,56 ]. A standardized personality inventory showed elevated scores across several psychological domains (e.g., anxiety, hypochondriasis, and social withdrawal), consistent with maladaptive personality traits and linked to pronounced fear of death, though findings lack replication [ 49 ]. Notably, 40% of family members experienced elevated distress, emphasizing the broader psychosocial impact [ 52 ].…”

“…Limited data are available. One study described denial and social withdrawal as coping strategies to potentially mute feelings and anxiety [ 49 ]. Two studies noted patients felt misunderstood, citing poor communication with others and inadequate social or expert support [ 53,54 ].…”