volume 275, issue 1-2, P279-283 2004
DOI: 10.1016/j.ijpharm.2004.01.037
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Abstract: We previously reported a method of preparing finely powdered green tea (PT), powder characteristics and release profiles of green tea components from PT. In this study, we performed formulation studies of PT tablets containing mitomycin C (MMC), expecting its combined antitumor effects with mitomycin C and green tea components. The hardness of PT tablets was low (22-50 N) and the disintegration time was about 180 min regardless of hardness or tabletting pressure (15-200 MPa). Perfiller-101 improved tablet char…

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