A diversidade do HIV-1: uma ferramenta para o estudo da pandemia

Abstract

HIV-1 is remarkable for the diversity of strains comprising the HIV/AIDS pandemic. In the last decade, classification of viral variants as groups, subtypes, and circulating recombinant forms (CRF) and the observation of specific mutational patterns have become powerful tools for studying viral molecular dynamics. Monitoring the worldwide distribution of HIV-1 diversity has been used in both epidemiological surveillance programs and in reconstructing the history of regional epidemics. Specific patterns of virus…