A descriptive study of tuberculosis case finding in private health care facilities in a South Indian district

Chadha, V. K.; Praseeja, P.; Gupta, J.; Ahmed, Javed; Sharada, M A; Srivastava, R. K.; Gowda, Usha; Magesh, V.; Singh, Sanjay; Suganthi, P; Lakshminarayana, K; Kumar, Prahlad

doi:10.5588/ijtld.14.0228

Cited by 5 publications

(3 citation statements)

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“…Bone TB has been suggested as an important cause of vertebral osteomyelitis and it is a common site of EPTB. 21 A study conducted in Private Medical College in India revealed that about 83% of all cases diagnosed were EPTB. 21 This could be due to availability of expertise and facilities for EPTB diagnosis.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Profile, Drug Utilization Pattern and Adverse Drug Reactions of Anti-tubercular Drugs at DOTS Center in a Tertiary Hospital

Chaudhary¹,

Sarraf

Bhattarai

et al. 2020

Nep. Med. Coll. J.

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Most of anti-tubercular drugs (ATD) cause various adverse drug reactions (ADRs) leading to significant morbidity which may have negative consequences on drug adherence and treatment outcome. The objectives of the study were to know the clinical profile of patients receiving ATD, to identify the pattern of ADRs caused by ATD and to know the drug utilization pattern (DUP) in different types of tuberculosis (TB). A prospective observational study was conducted among patients diagnosed with TB at DOTS center in BPKIHS from June 2017 to May 2018 and occurrence of any ADRs were detected during their monthly visit. Descriptive statistics were used to analyze the data. A total of 126 tuberculosis patients were on ATD therapy during the study period. Seventy five patients (59.5%) were male. Most of the patients (44.4%) belonged to age group 21-40 year. Pulmonary TB (66.7%) was more common than extra-pulmonary TB. Multi-drug resistant TB was detected in 4 patients (3.2%). Seventy one patients (56.3%) were found to be smear positive for acid fast bacilli. First line ATD was given to 122 patients (96.8%). Out of 126 patients, 116 (92.1%) reported occurrence of at least one ADR. A higher number of ADRs were observed in male (68.3%). Change in urine color was the most common ADR (92.9%) followed by nausea and vomiting (39.7%). Further studies covering different regions of Nepal are needed to generalize the findings.

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Section: Discussionmentioning

confidence: 99%

“…21 A study conducted in Private Medical College in India revealed that about 83% of all cases diagnosed were EPTB. 21 This could be due to availability of expertise and facilities for EPTB diagnosis. MDR-TB cases were detected in 3.17% patients in our study.…”

Section: Discussionmentioning

confidence: 99%

Clinical Profile, Drug Utilization Pattern and Adverse Drug Reactions of Anti-tubercular Drugs at DOTS Center in a Tertiary Hospital

Chaudhary¹,

Sarraf

Bhattarai

et al. 2020

Nep. Med. Coll. J.

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“…On the other hand, this is likely to be low, as the selected DMCs are located at the headquarters of their respective TUs, where the majority of the district's PPs have their practice. Another limitation is that as data were extracted from DMC laboratory registers, referred cases who did not reach the DMCs were not captured, hence potentially leading to an underesti- 21 It should be noted, however, that at the time of the study histopathology was available only in the private sector in the district, making referral to the RNTCP for the diagnosis of extra-pulmonary TB not meaningful to explore. The WHO recommends that the source of referral and place of treatment be routinely recorded and reported to assess PSP participation in national TB programmes.…”

Section: Discussionmentioning

confidence: 99%

Private practitioners' contributions to the Revised National Tuberculosis Control Programme in a South Indian district

Yellappa

Battaglioli

Gurum³

et al. 2016

int j tuberc lung dis

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Pretreatment loss to follow-up of tuberculosis patients in Chennai, India: a cohort study with implications for health systems strengthening

et al. 2018

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BackgroundPretreatment loss to follow-up (PTLFU) is a barrier to tuberculosis (TB) control in India’s Revised National TB Control Programme (RNTCP). PTLFU studies have not been conducted in India’s mega-cities, where patient mobility may complicate linkage to care.MethodsWe collected data from patient registries for May 2015 from 22 RNTCP designated microscopy centers (DMCs) in Chennai and audited addresses and phone numbers for patients evaluated for suspected TB to understand how missing contact information may contribute to PTLFU. From November 2015 to June 2016, we audited one month of records from each of these 22 DMCs and tracked newly diagnosed smear-positive patients using RNTCP records, phone calls, and home visits. We defined PTLFU cases as including: (1) patients who did not start TB therapy within 14 days and (2) patients who started TB therapy but were lost to follow-up or died before official RNTCP registration. We used multivariate logistic regression to identify factors associated with PTLFU.ResultsIn the audit of May 2015 DMC registries, out of 3696 patients evaluated for TB, 1273 (34.4%) had addresses and phone numbers that were illegible or missing. Out of 344 smear-positive patients tracked from November 2015 to June 2016, 40 (11.6%) did not start TB therapy within 14 days and 36 (10.5%) started therapy but were lost to follow-up or died before official RNTCP registration, for an overall PTLFU rate of 22.1% (95%CI: 17.8%—26.4%). Of all PTLFU patients, 55 (72.4%) were lost to follow-up and 21 (27.6%) died before starting treatment or before RNTCP registration. In the regression analysis, age > 50 years (OR 2.9, 95%CI 1.4—6.5), history of prior TB (OR 3.9, 95%CI 2.2—7.1), evaluation at a high patient volume DMC (OR 3.2, 95% CI 1.7—6.3), and absence of legible patient contact information (OR 4.5, 95%CI 1.3—15.1) were significantly associated with PTLFU.ConclusionsIn an Indian mega-city, we found a high PTLFU rate, especially in patients with a prior TB history, who are at greater risk for having drug-resistance. Enhancing quality of care and health system transparency is critical for improving linkage of newly diagnosed patients to TB care in urban India.Electronic supplementary materialThe online version of this article (10.1186/s12879-018-3039-3) contains supplementary material, which is available to authorized users.

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A descriptive study of tuberculosis case finding in private health care facilities in a South Indian district

Abstract: The proportion of extra-pulmonary cases was higher in the medical college and nursing homes and that of retreatment cases was lower than in the RNTCP.

Cited by 5 publications

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Clinical Profile, Drug Utilization Pattern and Adverse Drug Reactions of Anti-tubercular Drugs at DOTS Center in a Tertiary Hospital

Clinical Profile, Drug Utilization Pattern and Adverse Drug Reactions of Anti-tubercular Drugs at DOTS Center in a Tertiary Hospital

Private practitioners' contributions to the Revised National Tuberculosis Control Programme in a South Indian district

Pretreatment loss to follow-up of tuberculosis patients in Chennai, India: a cohort study with implications for health systems strengthening

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