A dataset of diversity and distribution of rodents and shrews in China

Chen, Jinjin; Xu, Qiang; Wang, Tao; Meng, Fan-Fei; Li, Zhiwei; Fang, Li‐Qun; Wei, Liu

doi:10.1038/s41597-022-01422-2

Cited by 9 publications

(8 citation statements)

References 16 publications

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“…peninsulae compared to the other four species studied. These ve rodent species are widely distributed throughout Northern China (23), thus the viral community identi ed from the same species of rodents in Beijing might as well provide valuable insights into potential zoonotic pathogens in other region as well.…”

Section: Discussionmentioning

confidence: 99%

Virome characterization of field-collected rodents in suburban Beijing reveals a spectrum of emerging pathogens

Hu,

Tang,

Zhang

et al. 2024

Preprint

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Background Rodents serve as natural reservoirs and transmission hosts for numerous zoonotic viruses, which can cause a range of animal and human diseases, posing significant public health concerns. Analyzing the viral diversity harbored by rodents is crucial for early warnings of emerging infectious diseases. Results By conducting meta-transcriptomic sequencing on spleen samples obtained from 432 wild rodents across three habitats, we characterized the high-depth RNA virome of wild rodents representing 9 species of two prominent mammalian families (Cricetidae and Muridae) in suburban Beijing. The composition of virome varied significantly at the virus family level among the nine rodent species and three types of natural habitats. A total of 142 viral species associated with vertebrates (n = 133) and invertebrates (n = 9) were identified from 26 families, including 75 novel viruses and 67 known viruses, thereby substantially expanding our knowledge about the diversity of rodent virome. Among these, twenty-five viruses were classified as high-risk, including 8 zoonotic viruses and 17 spillover-risk viruses. Additionally, nine previously unreported viruses were discovered for the first time in China. Furthermore, thirty-three viruses exhibited species transmission potential and some had evolutionary significance. Conclusions These findings enhance our understanding of rodent virome in Suburban Beijing and suggest that there is vast array of undiscovered viruses within these rodent species in China. Understanding the composition of rodent virome might provide insights into the potential risk of zoonotic spillover to humans.

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Section: Discussionmentioning

confidence: 99%

Virome characterization of field-collected rodents in suburban Beijing reveals a spectrum of emerging pathogens

Hu,

Tang,

Zhang

et al. 2024

Preprint

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“…R. tanezumi was found to carry the largest number of zoonotic pathogen species (eight species), and it was distributed widespread in China [ 6 ]. However, due to the small number of animal samples collected in Inner Mongolia, R. tanezumi was captured in three provinces in our study, and the surveillance of R. tanezumi should be strengthened in the future.…”

Section: Discussionmentioning

confidence: 99%

“…China is a megadiversity country and harbours various rodents and shrews. The rodents and shrews belong to the RODENTIA and EULIPOTYPHLA orders, and there are 235 species of 12 families and 92 species of 3 families in the RODENTIA and EULIPOTYPHLA orders in China, respectively [6]. Rodents and shrews can transmit zoonotic pathogens to human directly when humans consume food, water, or air that is contaminated with faeces and bodies [7] or indirectly when humans are bitten by arthropod vectors [8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Zoonotic pathogens identified in rodents and shrews from four provinces, China, 2015–2022

Tian,

Jiang,

Liu

et al. 2023

Epidemiol. Infect.

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Rodents and shrews are major reservoirs of various pathogens that are related to zoonotic infectious diseases. The purpose of this study was to investigate co-infections of zoonotic pathogens in rodents and shrews trapped in four provinces of China. We sampled different rodent and shrew communities within and around human settlements in four provinces of China and characterised several important zoonotic viral, bacterial, and parasitic pathogens by PCR methods and phylogenetic analysis. A total of 864 rodents and shrews belonging to 24 and 13 species from RODENTIA and EULIPOTYPHLA orders were captured, respectively. For viral pathogens, two species of hantavirus (Hantaan orthohantavirus and Caobang orthohantavirus) were identified in 3.47% of rodents and shrews. The overall prevalence of Bartonella spp., Anaplasmataceae, Babesia spp., Leptospira spp., Spotted fever group Rickettsiae, Borrelia spp., and Coxiella burnetii were 31.25%, 8.91%, 4.17%, 3.94%, 3.59%, 3.47%, and 0.58%, respectively. Furthermore, the highest co-infection status of three pathogens was observed among Bartonella spp., Leptospira spp., and Anaplasmataceae with a co-infection rate of 0.46%. Our results suggested that species distribution and co-infections of zoonotic pathogens were prevalent in rodents and shrews, highlighting the necessity of active surveillance for zoonotic pathogens in wild mammals in wider regions.

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“…might have contributed to transmission. Though LayV cases were detected across two eastern provinces, cases could have occurred elsewhere, as shrews exhibit wide geographical distribution, including north-eastern and southern China [47,48], thus warranting expansion of surveillance within China and possibly beyond [49].…”

Section: Though 75% Of Emerging Infectious Diseases (Eids) Are Zoonot...mentioning

confidence: 99%

The Emergence of Novel Langya Henipavirus in China

Chen¹,

Quigley²

2022

Global Biosecurity

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A study published on 4 August 2022 was the first to report on human cases and disease emergence [1]. Disease or outbreakLangya henipavirus (LayV) OriginLayV was first detected as a phylogenetically distinct henipavirus in Qingdao, Shandong province, during an active surveillance study conducted between April 2018 -August 2021 in Shandong and Henan provinces, which recruited and monitored patients with acute fever and history of animal exposure [1]. Suspected SourceLayV is reportedly zoonotic, with shrews suspected to be the natural reservoir host [1]. Specifically, LayV was detected in Ussuri (Crocidura lasiura) and Asian lesser (Crocidura shantungensis) whitetoothed shrews (LayV RNA positivity rates of 52.1% and 20.0% respectively) [1].

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A dataset of diversity and distribution of rodents and shrews in China

Cited by 9 publications

References 16 publications

Virome characterization of field-collected rodents in suburban Beijing reveals a spectrum of emerging pathogens

Virome characterization of field-collected rodents in suburban Beijing reveals a spectrum of emerging pathogens

Zoonotic pathogens identified in rodents and shrews from four provinces, China, 2015–2022

The Emergence of Novel Langya Henipavirus in China

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