A cross-sectional study of olfactory and taste disorders among COVID-19 patients in China

Li, Jianhui; Sun, Yi; Li, Meirong; Hu, Yuan; Yang, Changliang; Huang, Chengcheng; Zhou, Fengjie; Chen, Ruiyao; Zhang, Leibo; Yu, Ning; Liu, Qiong; He, Jingjing; Zhou, Xuejun; Fu, Xiaobing; Yang, Shi‐Ming

doi:10.1186/s40779-021-00339-y

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…In a cross-sectional study in China involving 187 patients with confirmed severe COVID-19 infection, it is purported that the SARS-CoV-2 virus neuroinvades via olfactory sensory neurons, colonising olfactory bulb tissue. Increased expression of ACE2 in the nasopharynx may lead to an increased risk of olfactory and taste symptoms [35]. The authors also propose using olfactory or taste disturbance as an early-warning symptom to screen for patients potentially infected with COVID-19, especially in the absence of rhinitis.…”

Section: Effect On Organ Systemsmentioning

confidence: 99%

Pushing the frontiers of military medical excellence: updates, progress and future needs

Seah

Wang

2022

Military Med Res

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Since its establishment in 2014, MilitaryMedicalResearch has come a long way in becoming a premier journal for scientific articles from various different specialties, with a special emphasis on topics with military relevance. The field of military medicine may be obscure, and may not be readily encountered by the typical clinician on a day-to-day basis. This journal aims not only to pursue excellence in military research, but also keep current with the latest advancements on general medical topics from each and every specialty. This editorial serves to recap and synthesize the existing progress, updates and future needs of military medical excellence, discussing foremostly the unique traits of literature published in this journal, and subsequently presenting the discourse regarding wartime and peacetime medicine, the role of the military in a public health emergency, as well as wound healing and organ regeneration. Special attention have been devoted to military topics to shed light on the effects of Chemical, Biological, Radiological and Explosive (CBRE) warfare, environmental medicine and military psychiatry, topics which rarely have a chance to be discussed elsewhere. The interconnectedness between military combat and soldier physical and mental well-being is intricate, and has been distorted by pandemics such as coronavirus disease 2019 (COVID-19). This journal has come a long way since its first article was published, steadily contributing to the existing knowledge pool on general medical topics with a military slant. Only with continuous research and sharing, can we build upon the work of the scientific community, with hopes for the betterment of patient care.

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Section: Effect On Organ Systemsmentioning

confidence: 99%

Pushing the frontiers of military medical excellence: updates, progress and future needs

Seah

Wang

2022

Military Med Res

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“…24 Pada kalangan perempuan, gangguan penghidu secara signifikan lebih umum dibandingkan dengan laki-laki karena adanya gen ACE-2 yang terletak pada kromosom X dan memiliki tingkat ACE-2 yang lebih tinggi sehingga perempuan lebih mungkin terinfeksi COVID-19 dibandingkan laki-laki. 25 Hal ini didukung dengan adanya penelitian yang dilakukan di Harlan Laboratories, Indianapolis, yang menyatakan bahwa terdapat perbedaan aktivitas ACE dengan tingkat Angiotensin (1-7) terhadap jenis kelamin. Pada penelitian tersebut, korteks ginjal tikus normotensif pada betina memiliki aktivitas ACE yang lebih besar dan tingkat Angiotensin (1-7) daripada jantan.…”

Section: Jenis Kelaminunclassified

“…26 Selain itu, adanya pengaruh hormonal yang mengakibatkan indera penghidu perempuan lebih jelas berfluktuasi dan lebih sensitif dibandingkan laki-laki. 25…”

Section: Jenis Kelaminunclassified

Profil Pasien COVID-19 dengan Gangguan Penghidu di RSUP Dr. M. Djamil Padang Periode 1 Januari - 31 Desember 2021

Khotimah,

Rahman,

Tofrizal

2023

JOKLI

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Pendahuluan: Coronavirus disease 2019 atau COVID-19 merupakan wabah penyakit yang mudah menular dan menimbulkan beragam gejala. Gejala tersebut termasuk gangguan penghidu yaitu perubahan dalam kemampuan penghidu yang baru-baru ini dirasakan pasien COVID-19 dan dijadikan salah satu gejala COVID-19 yang patut diwaspadai oleh Centers for Disease Control and Prevention (CDC). Penelitian ini bertujuan untuk mengetahui profil pasien COVID-19 dengan gangguan penghidu di RSUP Dr. M. Djamil Padang. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif dengan jumlah sampel 73 pasien terkonfirmasi COVID-19 yang dirawat inap. Penelitian dilakukan di Instalasi Rekam Medis RSUP Dr. M. Djamil Padang pada bulan Juli – Oktober 2022. Data diambil dari rekam medis dengan metode simple random sampling. Hasil: Hasil penelitian ini didapatkan bahwa gangguan penghidu (58,9%) banyak terjadi pada pasien COVID-19. Rentang usia >65 tahun (23,3%) merupakan usia terbanyak dan lebih banyak dialami oleh perempuan (46,5%). Hasil D-dimer yang didapatkan mengalami peningkatan yang tinggi (74,4%) dan pasien banyak yang tidak memiliki komorbiditas (55,8%). Hasil rawatan (outcome) terbanyak yakni sembuh atau perbaikan (76,7%). Kesimpulan: Dari penelitian ini dapat disimpulkan bahwa pasien COVID-19 banyak yang mengalami gangguan penghidu dengan rentang usia >65 tahun. Proporsi jenis kelamin antara perempuan dan laki-laki tidak jauh berbeda. pasien merupakan perempuan. Kadar D-dimer ditemukan mengalami peningkatan dan banyak pasien yang tidak memiliki komorbiditas serta hasil rawatan terbanyak adalah pasien yang sembuh atau perbaikan.

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“…Among the most common symptoms of COVID-19 is taste dysfunction, which has a ranging clinical presentation 1 , 2 ]. Although its pathophysiology remains to be unclear [ 3 , 4 ], indirect damage to taste receptors by the viral infection of epithelial cells of the tongue and subsequent local inflammation seems to be the key factor [5] . Likewise, several treatments are proposed for COVID-19-related taste dysfunction; however, there is not enough information about efficacy and safety [3] .…”

Section: Introductionmentioning

confidence: 99%

A Brazilian multicenter pilot case series on the efficacy of photobiomodulation therapy for COVID-19-related taste dysfunction

Campos

Soares

Berlingieri³

et al. 2022

Photodiagnosis and Photodynamic Therapy

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A cross-sectional study of olfactory and taste disorders among COVID-19 patients in China

Cited by 3 publications

References 5 publications

Pushing the frontiers of military medical excellence: updates, progress and future needs

Pushing the frontiers of military medical excellence: updates, progress and future needs

Profil Pasien COVID-19 dengan Gangguan Penghidu di RSUP Dr. M. Djamil Padang Periode 1 Januari - 31 Desember 2021

A Brazilian multicenter pilot case series on the efficacy of photobiomodulation therapy for COVID-19-related taste dysfunction

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