There is very little research regarding the relationship between tests of executive functioning and actual functional ability in patients with dementia. Thirty-three patients diagnosed with dementia and 35 age-and education-matched healthy controls were administered tests of executing functioning and an observation-and informant-based activities of daily living (ADL). As expected, the results revealed that the controls outperformed the dementia patients on the executive and ADL tests. Additionally, executive functioning correlated significantly with aspects of functional ability in patients with dementia. This relationship was strongest for tests of verbal fluency (i.e., FAS) and a complex test of cognitive flexibility and reasoning ability (i.e., WCST). These findings suggest that some executive function tests are more sensitive than others for predicting specific functional abilities and that they may be most useful to healthcare professionals for treatment planning.
Keywordsactivities of daily living; functional ability; executive functioning; dementia; Alzheimer's disease It has been well established that tests of executive functioning are useful in characterizing frontal lobe brain lesions and various forms of dementia (Kramer et al., 2005;Kennedy, 2004;Razani, Boone, Miller, Lee, & Sherman, 2001; Walker, Meares, Sachdev, & Bodaty, Correspondence: Jill Razani, Ph.D., Department of Psychology, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330-8255, jill.razani@csun.edu, (818) 677-4623, (818) Most available studies have examined the relationship between ADLs and brief cognitive screening measures (e.g., MMSE) and ADLs (Vitaliano et al, 1984;Winograd, 1984) and have generally found strong correlations (Ford, Haley, Thrower, West, & Harrell, 1996;Reed, Jagust, & Seab, 1989;Warren et al., 1989). Similarly, few studies have examined the relationship between ADLs and larger neuropsychological test batteries. Cahn-Weiner et al. (2000) found that executive measures accounted for more variance in ADL performance than demographic variables such as age, health status, and education level in a community-dwelling group of elderly. The authors suggest that of the cognitive domains assessed, decline in executive abilities associated with normal aging may be the best predictor of functional deterioration. Boyle et al. (2003) found that that executive dysfunction on the Dementia Rating Scale alone explained 17% of the variance in instrumental ADLs (e.g., handling finances, managing medications) in patient with Alzheimer's disease. However, the executive measures used in this study were brief and the ADL test was informant rated, which is less reliable than observation-based measures (Pearson, 2000). Back-Madruga et al. (2002) found that a group of frontal-variant Alzheimer's disease patients performed worse on ADL tasks than the typical Alzheimer's patients.In the most comprehensive study to date assessing cognitive functioning and ADLs, Farias, Harrell, Neumann, and Houtz (...