A contemporary evaluation of surgical outcome in neonates and infants undergoing lung resection

A contemporary evaluation of pulmonary function in children undergoing lung resection in infancy

“…After obtaining research ethics board approval (PED-07-034, 2850), patients who had undergone lung resection at younger than 12 months and who were previously identified from medical archives at both the Montreal Children's Hospital (MCH) and Centre Hospitalier Universitaire SainteJustine (HSJ) were asked to participate in the study [2]. All patients were considered for enrollment from this list if they were older than 5 years at the time of this study and if they met the inclusion criteria.…”

“…However, several recent reports have demonstrated the safety of lung resection in the infantile period [2,6,7]. Furthermore, waiting to resect congenital lung lesions until the patient demonstrates symptoms may lead to increased rates of complication and longer lengths of hospital stay [2,7]. Another major point of contention relates to a lack of contemporary data regarding the effects of lung resection on future pulmonary function.…”

“…Another major point of contention relates to a lack of contemporary data regarding the effects of lung resection on future pulmonary function. [2,8]. To further support our current practice philosophy, we sought to prospectively evaluate the pulmonary function of children who had lung resections at younger than 12 months, to assess its impact on future respiratory morbidity.…”

Prenatal and Postnatal Management of Congenital Pulmonary Airway Malformation

“…Some authors adopt an early resection strategy to avoid the onset of symptoms [4,15,98,99] since the safety of lung resection during the infantile period has been proven [41,98,100], while others adopt a conservative strategy, recognising the surgical risks and the potential of overtreatment [97,101,102,103], and surgery is only purposed after the patient becomes symptomatic with recurrent infections or pneumothorax [100,104]. Additionally, some authors recognise the potential for spontaneous resolution: in a study of 56 children with an antenatal diagnosis of CPAM, two CPAMs spontaneously resolved postnatally and ten resolved antenatally [104].…”

“…In asymptomatic patients following the neonatal period, a 3.2% complication rate was estimated, and occurred at a median age of 7 months [107]. In fact, recurrent infections may impose technical difficulties at the time of lung resection [98,100,108]. Furthermore, it has been shown that the infection alone may lead to pulmonary growth impairment [105].…”